Prof. John I. ANETOR

John I. Anetor, PhD (Ib.), FIMLS (Nig.), FIBMS (UK),   ERT, FACN, FRSC (UK)
Professor of Chemical Pathology/ Toxicology

John Anetor is basically a scientifically qualified Chemical Pathologist (Clinical Biochemist). Chemical pathology deals essentially with the biochemical basis of disease processes, their laboratory investigation and management.  John obtained his doctorate in Chemical Pathology (specializing in Toxicology & Micronutrient Metabolism) from the University of Ibadan, Nigeria and had his postdoctoral fellowship in the Department of Pathology at the Osaka City University Medical School, Osaka, Japan, under the supervision of Professor Shoji Fukushima, M.D, PhD.  He belongs to many learned societies and professional bodies. He is a European Registered Toxicologist (ERT) and a Fellow of the American College of Nutrition (FACN). He is a Fellow of the Royal Society of Chemistry (FRSC) of the United Kingdom. John Anetor is also a Fellow of the Institute of Biomedical Science of the United Kingdom, Member (FIBMS) and a Member of the Association for Clinical Biochemistry & Laboratory Medicine (ACB) of the United Kingdom. He is a member of the Association of Clinical Chemists of Nigeria (ACCN), a Fellow of the Institute of Medical Laboratory Science of Nigeria, Member of the Society of Toxicology (SOT) of the United States, foundation member of the West African Society of Toxicology (WASOT), where he is an adviser. He is also a member of the German Society for Minerals and Supplements (GMS) and a life member of the Environmental Mutagen Society of India (EMSI). John Anetor was a member of the National Committee on the removal of lead from Nigeria’s gasoline.  He is an honorary Specialist Adviser (Consultant) in chemical pathology to the University College Hospital (UCH), Ibadan, Nigeria. He is a Member of the Committee on Traceability in Laboratory Medicine (C-TLM) of the Scientific Division of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) (2015-2017). He is currently the Administrative Head of the Department of Biomedical Laboratory Science, College of Medicine,  University of Ibadan (2015-2019).  He conducts interdisciplinary research with many collaborators and has published extensively. He holds many editorial responsibilities both nationally and internationally. The main thrust of the line of investigation of Professor Anetor has been to advance the understanding of the toxic effects and long-term consequences of chemicals that are increasingly employed in domestic and work places and the environment, characterisation of their mechanisms of action and susceptibility determinants as well as amelioration. The central hypothesis of his research is that using nutritional intervention (including chemoprevention) largely through the interplay of the micronutrients; based on the antioxidant hypothesis, immunomodulatory and molecular repair mechanisms as well as redox signalling that many clinical states can be modulated for a favourable outcome. Data from his research group; Toxicology/ Micronutrient Pathobiology have provided new insights in to the mechanisms by which toxicants exert their deleterious effects; that the pathobiology of micronutrients is a major biochemical lesion underlying many pathologic and clinical states.  Their data also suggest that instead of focusing on high levels of exposure to toxicants alone; there is the need to simultaneously examine toxicant/ nutrient stoichiometric ratio as a determinant of toxicity. Other data from his research group have provided additional evidence that chemical exposure leads to oxidative stress and impairment of molecular repair mechanisms, culminating in genome instability, one of the defining features of the risk of carcinogenesis. This may in part provide explanations for the increasing prevalence of cancer in this environment (developing countries generally).  John Anetor strongly believes that this understanding would have profound impact on the evaluation of chemical toxicity and methods of conducting risk assessment, management and defining what is ‘safe’.  His concept may lead to a re-examination of a bulwark of toxicology; “the dose alone determines the poison” of Paracelsus. 

 

Curriculum Vitae

Research

Publications