Prof. Adebola E. ORIMADEGUN

Profile

 A E Orimadegun Photo

Name: Adebola E. ORIMADEGUN

Designation: Professor
Faculty: CLINICAL SCIENCES
Department:Institute of Child Health
Phone Number:08058266882

Google Scholar Profile

ORCID Profile

Email:

This email address is being protected from spambots. You need JavaScript enabled to view it.

This email address is being protected from spambots. You need JavaScript enabled to view it.

This email address is being protected from spambots. You need JavaScript enabled to view it.

This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Brief Biography:

Adebola Emmanuel Orimadegun joined the services of the Institute of Child Health, University of Ibadan as a Research Fellow I in March 2008 after working as a full-time Hospital Consultant Paediatrician at the University College Hospital, Ibadan, Nigeria from January 2007 to February 2008. He has risen through the ranks of Senior Research Fellow (2011) and Reader (2014) and became Professor of Paediatrics and Child Health in 2017. He is currently the Director of the Institute of Child Health at the University of Ibadan, Ibadan, Nigeria.

Adebola Emmanuel Orimadegun is a He has a varied background, including Bachelor of Medicine and Surgery (M.B;B.S) at the University of Ibadan and specialisation training (residency) in Paediatrics at the University College Hospital, Ibadan, Nigeria. He also holds the Master of Science (MSc.) and Doctor of Philosophy (Ph.D.) in Epidemiology at the University of Ibadan and a Master of Science (MSc.) in Clinical Trials at the London School of Hygiene and Tropical Medicine, United Kingdom.

Adebola has a long-standing commitment to the development of academics and research in child health. He began contributing to Paediatrics and Child Health education in 2003 as a Senior Registrar, teaching undergraduate medical students in the Department of Paediatrics and others as part of their clinical postings. He later became a hospital consultant in the same department and continued to teach immunization, childhood poisoning, malaria, and social paediatrics until he joined the Institute of Child Health (ICH), where he contributed to the development of postgraduate diploma in child health courses as well as postgraduate Master of Public Health (MPH) courses in Child and Adolescent Health. At ICH, he has undertaken a variety of roles, including Postgraduate Coordinator, Coordinator of the ICH Child Welfare Clinic, and Leader of the Child Health and Development Research Unit. Adebola also teaches selected topics in epidemiology, clinical trials, and research methodology in many departments in the Faculty of Public Health and Faculty of Clinical Sciences of the University of Ibadan. He has served on numerous academic committees, internal and external programme validation, and review panels, and he is a skilled and experienced external examiner in higher education. He is passionate about improving the student experience and translating research into practise through education to ensure the best possible healthcare for children.

Adebola’s research focuses on unravelling the drivers of morbidity and mortality as well as improving the outcomes of leading causes of hospitalisation in children. He has used his knowledge of epidemiological methods in a series of hospital and community-based studies to find out causes of malaria-related deaths and poor clinical outcomes. More than one-third of his publications contributed to knowledge in the field of malaria in children. Many of his malaria studies identified genetic biomarkers, defined some host responses to the infection, and contributed to improving the management of the disease. Among children with severe malaria, these markers included hepcidin, MAD20 alleles, msp-1, and human adhesion molecules at six different loci (ICAM-1, E-selectin exon 2, CD36 exon 10, and PECAM exon 3). Some of his research findings have already formed the basis for malaria treatment and understanding genetic markers of diseases. His investigation into the causes of child deaths was based on the need to plan targeted interventions to reduce high child mortality in Nigeria.

 

Research

Current Research and Capacity Building Projects including Grants

1.Title: Countdown to 2030 and Stunting Exemplars: the Nigeria Country Case Study

Funders: Bill & Melinda Gates Foundation” under “Grant Agreement Investment ID INV-003416” (the “Principal Agreement”) through the Global Child Health, The Hospital for Sick Children, Canada and

Brief Summary: This study is a multi-centre and multinational research involving 13 countries in Africa and six states (each from a geopolitical region) in Nigeria. The overarching goal of this project is to track progress towards addressing reproductive, maternal, newborn, child, and adolescent health (RMNCAH), nutrition and survival in Nigeria with focus on understanding and explaining how progress was achieved. The study will also explore national, state, and community level perspectives on the drivers of and barriers to stunting and wasting reduction in Nigeria, including the major contributing factors behind change over time. The findings have generated a systematic landscape of the major stunting-relevant policies and programs in Nigeria, with focus on both direct and indirect nutrition initiatives delivered inside and outside of the health sector. The first phase of the Nigeria component of this study has been completed and a dissemination meeting was held at Abuja on May 26, 2022. Several stakeholders including the Minister and Directors of the Federal Ministry of Health, civil societies, non-governmental organisations, and the media were in attendance.  Publications from the work are under review.

Role: Principal Investigator (Nigeria)

Collaborators: Prof. A. S. Jegede, Department of Medical Sociology, University of Ibadan.

Publications

  

SELECTED PUBLICATIONS (Recent 20 out of over 90 publications)

1. Orimadegun A. E., Dada-Adegbola H. O., Michael O. S., Adepoju A. A., Funwei R. E., Olusola F. I., Ajayi I. O., Ogunkunle O. O., Ademowo O. G., Jegede A. S., Baba E., Hamade P., Webster J., Chandroman D. and Falade C. O. 2022. Non-Malaria Causes of Fever among under-5 Children with Negative Results for Malaria Rapid Diagnostic Test in South-Western Nigeria. J Trop Pediatr(4). DOI: 10.1093/tropej/fmac061.

2. Amouzou A., Maïga A., Faye C. M., Chakwera S., Melesse D. Y., Mutua M. K., Thiam S., Abdoulaye I. B., Afagbedzi S. K., Ag Iknane A., Ake-Tano O. S., Akinyemi J. O., Alegana V., Alhassan Y., Sam A. E., Atweam D. K., Bajaria S., Bawo L., Berthé M., Blanchard A. K., Bouhari H. A., Boulhassane O. M. A., Bulawayo M., Chooye O., Coulibaly A., Diabate M., Diawara F., Esleman O., Gajaa M., Garba K. H. A., Getachew T., Jacobs C., Jacobs G. P., James F., Jegede A. S., Joachim C., Kananura R. M., Karimi J., Kiarie H., Kpebo D., Lankoandé B., Lawanson A. O., Mahamadou Y., Mahundi M., Manaye T., Masanja H., Millogo M. R., Mohamed A. K., Musukuma M., Muthee R., Nabié D., Nyamhagata M., Ogwal J., Orimadegun A., Ovuoraye A., Pongathie A. S., Sable S. P., Saydee G. S., Shabini J., Sikapande B. M., Simba D., Tadele A., Tadlle T., Tarway-Twalla A. K., Tassembedo M., Tehoungue B. Z., Terera I., Traoré S., Twalla M. P., Waiswa P., Wondirad N. and Boerma T. 2022. Health service utilisation during the COVID-19 pandemic in sub-Saharan Africa in 2020: a multicountry empirical assessment with a focus on maternal, newborn and child health services. BMJ Glob Health(5). DOI: 10.1136/bmjgh-2021-008069 PMC9062456.

3. Adepoju A. A., Akere A., Ogun G. O., Ogunbosi B. O., Asinobi A. O., Bello O., Orimadegun A. E., Allen S. and Akinyinka O. O. 2022. Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature. Paediatr Int Child Health(1): 29-35. DOI: 10.1080/20469047.2021.1936393.

4. Abdulraheem M. A., Ernest M., Ugwuanyi I., Abkallo H. M., Nishikawa S., Adeleke M., Orimadegun A. E. and Culleton R. 2022. High prevalence of Plasmodium malariae and Plasmodium ovale in co-infections with Plasmodium falciparum in asymptomatic malaria parasite carriers in southwestern Nigeria. Int J Parasitol(1): 23-33. DOI: 10.1016/j.ijpara.2021.06.003.

5. Orimadegun B. E., Odaibo G. O., Orimadegun A. E., Agbedana E. O. and Falade C. O. 2021. Malaria parasite density and plasma apolipoprotein A1 in symptomatic and asymptomatic infections in Nigerian children. J Vector Borne Dis(4): 311-316. DOI: 10.4103/0972-9062.318309.

6. Orimadegun A. E., Funwei R. I., Michael O. S., Ogunkunle O. O., Badejo J. A., Olusola F. I., Agede O., Anjorin O. E., Ajayi I. O., Jegede A. S., Ojurongbe O. and Falade C. O. 2021. Comparative evaluation of three histidine-rich Protein-2 based rapid diagnostic tests, microscopy and PCR for guiding malaria treatment in Ibadan, Southwest Nigeria. Niger J Clin Pract(4): 496-504. DOI: 10.4103/njcp.njcp_491_20.

7. Lagunju I. A., Labaeka A., Ibeh J. N., Orimadegun A. E., Brown B. J. and Sodeinde O. O. 2021. Transcranial Doppler screening in Nigerian children with sickle cell disease: A 10-year longitudinal study on the SPPIBA cohort. Pediatr Blood Cancer(4): e28906. DOI: 10.1002/pbc.28906.

8. Ibekwe T., Ibekwe P. and Orimadegun E. A. 2021. Third force in the treatment of COVID-19: A systematic review and meta-analysis. Ann Med Surg (Lond) 65: 102218. DOI: 1016/j.amsu.2021.102218 PMC8018907.

9. Atalabi O. M., Adekanmi A. J., Orimadegun A. E. and Akinyinka O. O. 2021. Ultrasonographic Hepatosplenic Parenchymal and Blood Flow Changes in Children with Acute Falciparum Malaria. West Afr J Med(5): 420-427.

10. Adepoju A. A., Adelaja A. O., Amoo A., Orimadegun A. E. and Akinyinka O. O. 2021. Edwardsiella ictaluri, an unusual cause of bacteraemia in a Nigerian child with acute bloody diarrhoea. Int J Res Med Sci(10): 3175-3178. DOI: 10.18203/2320-6012.ijrms20213951 PMC8516347.

11. Orimadegun A. E., Adepoju A. A., and Myer L. 2020. A Systematic Review and Meta-analysis of Sex Differences in Morbidity and Mortality of Acute Lower Respiratory Tract Infections Among African Children. Journal of Pediatrics Review(2): 65-78. DOI: 10.32598/jpr.8.2.65 PMC7544245.

12. Orimadegun A. E. 2020. Protocol and Researcher's Relationship with Institutional Review Board. Afr J Biomed Res(Suppl 2): 15-20. PMC7876614.

13. Ibekwe T. S., Fasunla A. J. and Orimadegun A. E. 2020. Systematic Review and Meta-analysis of Smell and Taste Disorders in COVID-19. OTO Open(3): 2473974x20957975. DOI: 10.1177/2473974x20957975 PMC7488903.

14. Brown B. J., Manescu P., Przybylski A. A., Caccioli F., Oyinloye G., Elmi M., Shaw M. J., Pawar V., Claveau R., Shawe-Taylor J., Srinivasan M. A., Afolabi N. K., Rees G., Orimadegun A. E., Ajetunmobi W. A., Akinkunmi F., Kowobari O., Osinusi K., Akinbami F. O., Omokhodion S., Shokunbi W. A., Lagunju I., Sodeinde O. and Fernandez-Reyes D. 2020. Data-driven malaria prevalence prediction in large densely populated urban holoendemic sub-Saharan West Africa. Sci Rep(1): 15918. DOI: 10.1038/s41598-020-72575-6 PMC7522256.

15. Orimadegun A. E. and Myer L. 2019. Sex-specific prevalence and trends in acute respiratory infection episodes among children less than 5 years in Nigeria. Niger J Clin Pract(11): 1590-1599. DOI: 10.4103/njcp.njcp_34_19.

16. Falade C. O., Orimadegun A. E., Michael O. S., Dada-Adegbola H. O., Ogunkunle O. O., Badejo J. A., Funwei R. I., Ajayi I. O., Jegede A. S., Ojurongbe O. D., Ssekitooleko J., Baba E., Hamade P., Webster J. and Chandramohan D. 2019. Consequences of restricting antimalarial drugs to rapid diagnostic test-positive febrile children in south-west Nigeria. Trop Med Int Health(11): 1291-1300. DOI: 10.1111/tmi.13304.

17. Orimadegun A. E., Orimadegun B. E. and Bamgboye E. A. 2018. Short-term Persistence of Protective Maternally Acquired Immunity in Neonates Delivered by Primiparous Women in Ibadan, Nigeria. Ethiop J Health Sci(5): 547-554. DOI: 10.4314/ejhs.v28i5.5 PMC6308770.

18. McMillan A., Renaud J. B., Burgess K. M. N., Orimadegun A. E., Akinyinka O. O., Allen S. J., Miller J. D., Reid G. and Sumarah M. W. 2018. Aflatoxin exposure in Nigerian children with severe acute malnutrition. Food Chem Toxicol 111: 356-362. DOI: 1016/j.fct.2017.11.030.

19. Orimadegun A. E., Orimadegun B. E. and Bamgboye E. A. 2017. Non-protective immunity against tetanus in primiparous women and newborns at birth in rural and urban settings in Ibadan, Nigeria. Pan Afr Med J(Suppl 3): 26. DOI: 10.11604/pamj.supp.2017.27.3.11869 PMC5745943.

20. Balogun F. M., Alohan A. O. and Orimadegun A. E. 2017. Self-reported sleep pattern, quality, and problems among schooling adolescents in southwestern Nigeria. Sleep Med 30: 245-250. DOI: 1016/j.sleep.2016.11.013.

Supervision

CANDIDATES SUPERVISED AND RESEARCHERS MENTORED:

1. Master Of Philosophy (MPhil.): One (1)

2. MPH Child and Adolescent Health, University of Ibadan: Twenty-four (24)

3. Professional Fellowship in Paediatrics: Twelve (12)

 CURRENT SUPERVISION:                                                                    

1. MPH Child and Adolescent Health, University of Ibadan: Three (3)

2. Doctor of Philosophy (PhD): One (1)

3. Professional Fellowship in Paediatrics: One (1)

Grants

Not Available

Social Media Handle

 Facebook: Profile Link  LinkedInProfile Link  TwitterProfile Link
 Instagram: Profile Link  YouTubeProfile Link
Pinterest: Profile Link


Social Links

Get In Touch