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Name: Olusola O. OLAWOYE
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Designation: Reader
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Faculty: CLINICAL SCIENCES
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Department: Ophthalmology
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Phone Number: +234 8023890063
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Biography:
Dr. Olusola Olawoye graduated as a medical doctor from the University of Jos Nigeria in 1998. She completed her fellowship in Ophthalmology at the University College Hospital Ibadan Nigeria in 2008 when she became a fellow of both the National Postgraduate Medical College of Nigeria and the West African College of Surgeons in Ophthalmology. She completed a Masters in Epidemiology and Medical Statistics from the University of Ibadan in 2011 and obtained a PhD in Clinical Ophthalmology at the same University in 2021. She subsequently completed another PhD at the Queens University Belfast United Kingdom in 2023. She has a clinical fellowship in Glaucoma from both the New York Eye and Ear Infirmary and the Samsung Medical Centre Seoul South Korea. She also obtained a certificate in clinical research after a one-year training at the Harvard’s Medical School. Boston in 2019. She also obtained a certificate in randomized controlled trials from the Oxford University London in 2022. Olusola is a clinician–scientist with clinical and research experience dedicated to low-cost screening of glaucoma in low-resource settings, epidemiology, genetics and management of glaucomas. She has published several papers in high-impact journals in the glaucoma specialty in Sub-Saharan Africa. She was one of the first to pioneer the use of glaucoma drainage devices in Nigeria with a novel tube implant. He has participated in several international programs to advance glaucoma care in Africa and other LMICs. She was an active participant and contributor to the 9th and 10th consensus on childhood glaucomas and screening for glaucoma and also an active contributor to the global International Council of Ophthalmology guidelines for glaucoma eye care. She is currently a co-investigator in the Eyes of Africa project: the genetics of blindness study, a multicenter study in Sub-Saharan Africa, polygenic risk scores in glaucoma genetics in African populations, and low-cost glaucoma screening in West Africa. She is a member of the education committee of the World Glaucoma Association (WGA) and the Examination committee of the International Council of Ophthalmology. She is an Examiner at both the West African College of Surgeons and the National Postgraduate Medical College examinations in Ophthalmology, the Secretary General of the Ophthalmological Society of Nigeria, the Vice Chairman of the Glaucoma Society of Nigeria and the Deputy Chair of the Medical Advisory Committee (Clinical Services) in her Hospital. Olusola is a committed teacher, a hard-working researcher and a passionate clinician. She was a member of the Board of the Governors World Glaucoma Association (WGA) between 2015 -2019 representing Africa. She is currently a member of the Board of Council of the World Glaucoma Association. |
Completed
1. Evaluation of Community Eye Outreach Programs for Early Glaucoma
2. Detection in Nigeria
3. Patient Satisfaction with Cataract Surgery and Posterior Chamber
4. Intraocular Lens implantation at the University College Hospital Ibadan and St Mary’s Catholic Eye Hospital Ago-Iwoye, Nigeria
5. Exfoliation Syndrome in Nigeria
6. Outcome of Trabeculectomy Surgery in Ibadan
7. Genetics of Juvenile Open Angle Glaucoma patients
8. Glaucoma Drainage Devices in Ibadan
9. Severity and Treatment Acceptability of Glaucoma Therapy (STAGE)
10. Social Construction of Blindness
1. Olawoye, O.O., Ashaye, A.O., Teng C.C., Liebman, J., Ritch, R. and Ajayi, B.G.K. (2012). Exfoliation Syndrome in Nigeria. Middle East African Journal of Ophthalmology Vol.19. No.4:405-409pp (Saudi Arabia) (Contribution: 50%)
2. Olawoye, O.O., Fawole, O.I., Teng, C.C. and Ritch, R.R. (2013). . Evaluation of community eye outreach programs for early glaucoma detection in Nigeria. Clinical Ophthalmology Vol.7:1753–1759.pp (New Zealand) (Contribution: 60%)
3. Ashaye, A.O., Ashaolu, O.O., Komolafe, O.O., Ajayi, B.G., Olawoye, O.O., Olusanya, B.A. and Adeoti, C. (2013). Prevalence and types of glaucoma among an indigenous African population in south western Nigeria. Investigative Ophthalmology and Visual Science Vol.54. No.12:7410-7416 pp (United States of America) (Contribution: 20%)
4. Olawoye, O.O., Lee, M., Kuwayama, Y. and Kee, C. (2015). Fornix based trabeculectomy with Mitomycin C using the horizontal conjunctival suture technique. Journal of Glaucoma Vol.24. No.6:455-9pp (United States of America) (Contribution: 60%)
5. Olawoye O, Kizor-Akaraiwe N, Pons J, Sarimiye T, Washaya J, Hughes S, Ashaye A, Garba F, Gessesse GW, Chitedze R, Ibanga A, Saka V, Agre J, Mahdi A, Ogunro A, Budengeri P, Ajibode HA, Tamrat L, Onakoya A, Okeke S, Hulley JA, Giorgis A, Onyekachi IW, Okosa CC, Ogbonnaya C, Abdulsalam S, Fowobaje K, Cook S, Lawrence S, Macheka B, Chan VF, Blanco AA, Congdon N, Realini T; STAGE Research Group. Clinical Characteristics and Stage at Presentation of Glaucoma Patients in Sub-Saharan Africa. J Glaucoma. 2022 Sep 1;31(9):717-723. doi: 10.1097/IJG.0000000000002068. Epub 2022 Jun 27. PMID: 35758429.
6. Aung, T., Ozaki, M., Lee, M.C., Schlötzer-Schrehardt, U., Thorleifsson, G., ., ., ., Olawoye, O.O. and Khor,C.C. (2017). Worldwide genetic association study of exfoliation syndrome identifies highly protective rare 2 variants at LOXL1 and five new common-variant susceptibility loci. Nature Genetics Vol.49. No.7:993-1004pp (United States of America) (Contribution: 20%)
7. Olawoye O, Salami KK, Azeez A, Adebola P, Sarimiye T, Imaledo J, Realini T, Hauser MA, Ashaye A. The social construction of genomics and genetic analysis in ocular diseases in Ibadan, South-western Nigeria. PLoS One. 2022 Dec 1;17(12):e0278286. doi: 10.1371/journal.pone 0278286. PMID: 36454870; PMCID: PMC9714877
8. Olawoye, Olusola*,†; Washaya, Jennifer; Gessesse, Girum W.§; Balo, Komi∥; Agre, Jeremie; Macheka, Boniface; Akaraiwe, Nkiru Kizor**,; Pons, Jonathan; Sarimiye, Tarela*; Ashaye, Adeyinka*; Garba, Farouk§§; Chitedze, Richard; Ibanga, Affiong; Mahdi, Abdull; Ogunro, Adunola; Budengeri, Patrick; Ajibode, Haroun Adetunji; Tamrat, Lemlem§§§; Onakoya, Adeola; Okeke, Suhanyah; Giorgis, Abeba T.; Okosa, Chimdi Chuka; Fowobaje, Kayode; Cook, Stephen; Lawrence, Scott; Chan, Ving Fai; Blanco, Augusto Azuara†; Congdon, Nathan†,; Realini, Tony; The STAGE Research Group. Glaucoma Treatment Patterns in Sub-Saharan Africa. Journal of Glaucoma ():10.1097/IJG.0000000000002273, July 21, 2023. | DOI: 10.1097/IJG.0000000000002273
9. Olawoye OO, Ha TH, Pham N, Nguyen L, Cherwek DH, Fowobaje KR, Ross C, Coote M, Chan VF, Kahook M, Peto T, Azuara-Blanco A, Congdon N. Impact of a short online course on the accuracy of non-ophthalmic diabetic retinopathy graders in recognising glaucomatous optic nerves in Vietnam. BMJ Open. 2023 Nov 9;13(11):e076623. doi: 10.1136/bmjopen-2023-076623. PMID: 37945295; PMCID: PMC10649381.
10. Olawoye OO, Fawole O, Ashaye AO, Chan VF, Azuara-Blanco A, Congdon N. Effectiveness of community outreach screening for glaucoma in improving equity and access to eye care in Nigeria. Br J Ophthalmol. 2023 Jan;107(1):30-36. doi: 10.1136/bjophthalmol-2021-319355. Epub 2021 Aug 6. PMID: 34362773.
11. Oluwaniyi, A.T., Olawoye, O., Sarimiye, T.F. and Ajayi, B.G. (2023). Comparison of ocular biometry in primary open angle glaucoma and non-glaucoma in South West Nigeria. Journal of the West African College of Surgeons Vol.13.No.2:37-44
12. Gbadegesin, T.M., Olawoye, O., Sarimiye, T.F., Idowu, O.O. and Ajayi, B.G. (2023). Amsler grid versus 10-2 test in primary open angle glaucoma. Journal of the West African College of Surgeons Vol.13.No.2:92-99
13. Olawoye, O.O., Ashaye, A.O., Teng C.C., Liebman, J., Ritch, R. and Ajayi, B.G.K. (2012). Exfoliation Syndrome in Nigeria. Middle East African Journal of Ophthalmology Vol.19. No.4:405-409pp (Saudi Arabia) (Contribution: 50%)
14. Olawoye, O.O., Fawole, O.I., Teng, C.C. and Ritch, R.R. (2013). . Evaluation of community eye outreach programs for early glaucoma detection in Nigeria. Clinical Ophthalmology Vol.7:1753–1759.pp (Australia) (Contribution: 60%)
15. Olawoye, O.O. and Sarimiye, T.S. (2013). Spectrum of Glaucoma Presentation in a Nigerian Tertiary Hospital. Nigerian Journal of Ophthalmology Vol.21.No.2:17-21pp (Nigeria) (Contribution: 80%)
16. Keel S, Lingham G, Misra N, Block S, Bourne R, Calonge M, Cheng CY, Friedman DS, Furtado JM, Khanna R, Mariotti S, Mathenge W, Matoto E, Müeller A, Rabiu M, Rasengane T, Resnikoff S, Wormald R, Yasmin S, Zhao J, Evans JR, Cieza A; Olawoye OO. Package of Eye Care Interventions Development Group. Toward Universal Eye Health Coverage-Key Outcomes of the World Health Organization Package of Eye Care Interventions: A Systematic Review. JAMA Ophthalmol. 2022 Dec 1;140(12):1229-1238. doi: 10.1001/jamaophthalmol.2022.4716. PMID: 36394836.
17. *Gharahkhani, P., Jorgenson, E., Hysi, P., Khawaja, P., Pendergrass, S., Han, X., Rouhana, J., Hamel, A.R., Robert, P., Choquet, H., Qassim, A., Josyula, S., Cooke-Bailey, J., Bonnemaijer, P., , Siggs, O.R., Young, TL., Ashaye, A., Olawoye, O.O., Williams, S.E., Akafo, S., Ramsay, M., Hashimoto, K., Foster, P.J., Khaw, P.T., Morgan, J.E., Strouthidis, M.G., Kraft, P., Kang, J.H., Pang, C.P., Pasutto, F., Mitchell, P., Lotery, A.J., Kubo, M., Cheng, C.Y., Craig, J.E., MacGregor S. and Wiggs, J.L. (2021). Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature Communications Vol.12:1258-1274.pp (United States of America) (Contribution: 20%)
18. *Ogunleye, O., Olawoye, O.O., Sarimiye, T.F., Bekibele, C.O. and Ashaye, A.O. (2021). The Effect of Direct Health Education on the Uptake of Screening by First Degree Relatives of Glaucoma Patients in Nigeria Journal of Glaucoma Vol.30. No.5:395-401.pp (United States of America) (Contribution: 50%) (Corresponding author)
19. *Olatunji, O.P., Olawoye, O.O. and Ajayi. B. (2020). Correlation and Agreement Between Water Drinking Test and Modified Diurnal Tension Curve in Untreated Glaucoma Patients in Nigeria. Journal of Glaucoma Vol.29.No.6:498-503.pp (United States of America) (Contribution: 50%) (Corresponding Author)
20. *Hauser, M.A., Allingham, R.R., Aung, T., Van-Der- Heide, C.J., Taylor, K.D., Rotter, J.I., Wang, S.J., Olawoye, O.O., Weinreb, R.N., Ashley-Koch, A.E., Fingert, J.H. and Khor, C.C. (2019). Association of Genetic Variants with Primary Open-Angle Glaucoma Among Individuals With African Ancestry Journal of American Medical Association Vol.322. No. 17:1682-1691pp (United States Of America) (Contribution: 20%).
CURRENT STUDENTS
Doctoral Level
1. Evaluation of stereoacuity in glaucoma patients, suspects, and control at the University College Hospital, Ibadan
Adebusoye, S.
National Postgraduate Medical College (M.D. degree)
2. Peak intraocular pressure time and fluctuation parameters during water drinking test and its relationship with glaucoma severity
Ogunbiyi, A.
National Postgraduate Medical College (M.D. degree)
Fellowship Level
1. Relationship Between Medication Adherence and Eye Drop Instillation Technique Among Primary Open Angle Glaucoma Patients In Federal Medical Center, Lokoja
Afolayan Deborah Fisayo
National Postgraduate Medical College
2. Association Between Severity Of Glaucoma And Quality Of Life In Primary Open Angle Glaucoma Patients At Ekiti University Teaching Hospital
Adeleke Funmilayo Olamide
National Postgraduate Medical College
PREVIOUS STUDENTS (Selected)
Masters Level
1. Compliance with medical therapy in glaucoma patients attending Bowen University Ogbomosho
Dr Akinsola Aina
College of Medicine University of Ibadan
Doctoral level
2. Exploring the Ocular Biometric Changes after Trabeculectomy in Nigerian Adult Glaucoma Patients
Onebunne, E.
National Postgraduate Medical College (M.D. degree)
Fellowship
1. The effect of education and telephone reminders on adherence to use of glaucoma medications amongst glaucoma patients at University College Hospital, Ibadan, Nigeria
Ata, A. S.
West African College of Surgeons
2. The Effect of Direct Health Education On the Uptake of Screening by First Degree
Relatives of Primary Open Angle Glaucoma Patients in Ibadan
Dr. Ogunleye O
West Africa College of Surgeons (Ophthalmology)
3. Evaluation of central glaucomatous visual field defects using standard automated perimetry and Amsler grid
Dr. Gbadegesin Temitope
National Postgraduate Medical College
4. Comparative Evaluation of Peripapillary Retinal Nerve Fibre Layer Thickness in Myopes and Emmetropes at the University College Hospital Ibadan
Dr. Ibiyemi AA
West African College of Surgeons
5. Comparison Of Ocular Biometry In Primary Open Angle Glaucoma And Controls In South West Nigeria.
Dr. Oluwaniyi
National Postgraduate Medical College
Current Research and Capacity Building Projects including Grants
1. Title: Eyes of Africa – Genetics of blindness
Funder: NIH and H3Africa
Brief Summary: This is a multi-country and multicentre hospital based prospective case control study is aimed at identifying new susceptibility genes for primary open-angle glaucoma (POAG) in order to lay the foundation for novel therapeutic intervention. The aims to enrol 12,000 POAG cases and controls from multiple existing sites in sub-Saharan Africa to add to our existing, genotyped dataset of African ancestry containing 5000 cases and controls. Our preliminary data from the existing dataset clearly shows that the genetic susceptibility loci found in Caucasians and Asians are NOT the primary associations for POAG in Africans. Successful completion of this aim will reveal the unique genetic underpinnings of glaucoma in Africa and suggest new targets for therapeutic intervention.
Role: Co-Investigator
Collaborators: Professor Adeyinka Ashaye, Dr Tarela Sarimiye, and Hauser M.A.
2. Title: Effect of Selective Laser Trabeculoplasty in reducing intraocular pressure in Open Angle Glaucoma:
Funder: CARTA
Brief Summary: This is a randomized controlled trial. This study sets out to conduct an internal pilot for a full trial to test the hypothesis that translimbal Direct Selective Laser Trabeculoplasty (DSLT) is effective and not inferior to conventional Selective Laser Trabeculoplasty (SLT) in reducing intraocular pressure (IOP) in Open Angle Glaucoma (OAG) in Nigeria. A total of hundred and sixty patients will be recruited, eighty patients in each treatment arm of either translimbal Direct Selective Laser Trabeculoplasty (DSLT) or conventional Selective Laser Trabeculoplasty (SLT) treatment. Participants will be required to visit the clinic for follow up at least 7 times (on day 0, 1,7,30,90,180, and 365) within the 1-year period of the study.
Role: Principal Investigator
Collaborators: Sarimiye, T, Olusanya B., and Realini T.
3. Title: Low Cost Glaucoma Screening in West Africa
Funder: BrightFocus
Brief Summary: West African populations have the highest prevalence of glaucoma in the world—7-8% of the population over 40 years of age is affected. Glaucoma in this population is aggressive, with early onset and rapid progression, with some individuals presenting at the clinic at age 30 already blind in one eye. Affected individuals have no symptoms until substantial visual field loss has occurred when clinical intervention does not have a good prognosis. The use of non-ophthalmologists and low-cost imaging cameras to conduct screening in low-resource settings is particularly important, scalable, realistic and likely to be cost-effective. We hypothesize that an accurate approach to the detection of glaucoma implemented at community outreaches in Nigeria and indeed the rest of sub-Saharan Africa could be a game-changer in reducing the burden of a leading cause of blindness for which no proven population screening models currently exist globally. The current study aims to assess the diagnostic accuracy (sensitivity and specificity) of fundus photos to detect glaucoma using images captured by low-cost devices at outreaches in Oyo State and surrounding environs.
Role: Institutional PI
Collaborators: Prof Adeyinka Ashaye, Dr Tarela Sarimiye
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