Name: Williams O. BALOGUN Email: This email address is being protected from spambots. You need JavaScript enabled to view it. Alternate Email Address 1: This email address is being protected from spambots. You need JavaScript enabled to view it. Biography: Dr. Williams Balogun is a Senior Lecturer in the Department of Medicine of the College of Medicine, University of Ibadan, and a Consultant Physician and Endocrinologist at the University College Hospital (UCH), Ibadan. He holds MBBS and MSc (Chemical Pathology/Endocrinology) degrees of the University of Ibadan, a Fellow of West African College of Physicians (FWACP) and American College of Endocrinologists (FACE). He is the founding Editor-in-Chief of Annals of Ibadan Postgraduate Medicine and currently, it’s Editorial Consultant. His area of research interest lies in the novel combination of genotypic and phenotypic information to achieve precision in the diagnosis, classification, prevention and treatment of age-related diabetes, including early-onset type 2 diabetes, monogenic diabetes and diabetes in the ageing. Current Research and Capacity Building Projects including Grants 1. Title: Genetic testing for accurate diabetes differentiation in Nigeria Completed Research 1. Strategies for Improving Diabetes Care in Nigeria (SIDCAIN) I (2008 – 2014) & II (2013 - 2016) 2. Diabetes in the Younger Adults (DIYA) Study 3. Glycated haemoglobin-based Prediabetes Study 4. African American Diabetes Mellitus Study SELECTED PUBLICATIONS Chapters in Books: 1. O. Balogun Simplified Complete Handbook on Diabetes: (Chapter 15) Edited by C.O. Alebiosu and O.B. Familoni (2007) 2. AO Falase & OO Akinkugbe A Compendium of Clinical Medicine (Section on Endocrinology) 3. Strategies for Improving Diabetes Care in Nigeria (SIDCAIN) (2010) Diabetes & Hypertension Treatment Guidelines for Health Workers Samdavies; ISBN: 978-978-48522-3-4 Selected Journal Publications 4. (2019). Ekoru E., Doumatey A., Bentley A. R., Chen G., Zhou J., Shriner D., Fasanmade O., Okafor G., Eghan B., Agyenim-Boateng K., Adeleye J., Balogun W., et al. Type 2 diabetes complications and comorbidity in Sub-Saharan Africans. EClinicalMedicine 5. (2023). Balogun W.O., Emuze M. E., A Lawal, EI Ekhaiyeme. Cardio Metabolic Indices among Ageing Nigerians with Type 2 Diabetes in a Tertiary Health FacilityJ Clin Mol Endocrinol 6. (2023). Ajayi IO, Balogun WO, Olopade OB, Ajani GO, Soyoye DO, Bolarinwa OA, Olamoyegun MA, Alatishe-Muhammad BW, Odeniyi IA, Odukoya O, Fasanmade OA, Diyaolu FP, Otrofanowei E, Akase I, Agabi PO, Adejimi A, Ajetunmobi OA, Durowade KA, Gabriel-Alayode EO, Ibrahim AO, Ezekpo OO, Elegbede TO, Lamidi AO, Owolabi FA, Yusuf AO, Adetunji TA, Ogunmodede AJ, Ameen AH, Biliaminu AS, Nasiru S. Front Endocrinol (Lausanne) 7. (2020). Balogun WO, Uloko AE, Owolabi MO. Atypical Diabetes Presentations in Sub-Saharan Africa Classification Puzzle and Possible Role of Precision Medicine. West African Journal of Medicine 8. (2020). Balogun W.O, Onasanya A.S and Azeez T.A. Prevalence and clinical characteristics of Nigerian patients with early-onset type 2 diabetes. Nigerian Journal of Medicine 9. (2019). Adeyemo AA, Zaghloul NA, Chen G, Doumatey AP, Leitch CC, Hostelley TL, Nesmith JE, Zhou J, Bentley AR, Shriner D, Fasanmade O, Okafor G, Eghan B Jr, Agyenim-Boateng K, Chandrasekharappa S, Adeleye J, Balogun W, Owusu S, Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C; South Africa Zulu Type 2 Diabetes Case-Control Study, Collins F, Dunston G, Rotimi CN (2019). ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. Nature Communications 10. (2018). Akpalu J, Yorke E, Ainuson-Quampah J, Balogun W and Yeboah K. Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana. BMC Psychiatry 11. (2018). Balogun WO, Uloko AE, Ipadeola A, Enang O, Adamu AN, Mubi BM, Okafor CI, Odeniyi I, Lawal IU, Adeleye JO and Fasanmade OA. Prevalence of Obesity and Ethno-Geographic Variation in Body Sizes of Nigerians With Type 2 Diabetes Mellitus- A Multi-Centre Study. Nigerian Journal of Medicine 12. (2016). Adebamowo SN, Adeyemo AA, Tekola-Ayele F, Doumatey AP, Bentley AR, Chen G, Zhou J, Shriner D, Fasanmade OA, Okafor G, Eghan Jr. B, Agyenim-Boateng K, Adeleye J, Balogun W, Amoah AG, Owusu S, Acheampong J, Johnson T, Oli J, Adebamowo CA and Rotimi CN (2016). Impact of Type 2 diabetes on Impaired Kidney Function in Sub-Saharan African Population. Frontiers in Endocrinology 13. (2015) Akinlade KS, Agbebaku SO, Rahamon SK, Balogun WO. Vitamin B12 Levels In Patients With Type 2 Diabetes Mellitus On Metformin Annals of Ibadan Postgraduate Medicine 14. (2015). Adeyemo AA, Tekola-Ayele F, Doumatey AP, Bentley AR, Chen G, Huang H, Zhou J, Shriner D, Fasanmade O, Okafor G, Eghan B Jr, Agyenim-Boateng K, Adeleye J, Balogun W, Elkahloun A, Chandrasekharappa S, Owusu S, Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C, Collins F, Dunston G and Rotimi CN. Evaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans. Frontiers in Genetics 15. (2013). Alebiosu CO, Familoni OB, Ogunsemi OO, Raimi TH, Balogun WO, Odusan O, Oguntona SA, Olunuga T, Kolawole BA, Ikem RT, Adeleye JO, Adesina OF, Adewuyi PA. Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321). Indian Journal of Endocrinology & Metabolism 16. (2013) Balogun WO, Gureje O. Self-reported incident type 2 diabetes in the Ibadan study of ageing: relationship with urban residence and socioeconomic status. Gerontology. 17. (2012). Bentley AR, Doumatey AP, Chen G, Huang H, Zhou J, Shriner D, Jiang C, Zhang Z, Liu G, Fasanmade O, Johnson T, Oli J, Okafor G, Eghan BA Jr, Agyenim-Boateng K, Adeleye J, Balogun W, Adebamowo C, Amoah A, Acheampong J, Adeyemo A, Rotimi CN. Variation in APOL1 Contributes to Ancestry-Level Differences in HDLc-Kidney Function Association. International Journal of Nephrology 18. (2012). Doumatey AP, Zhou J, Huang H, Adeleye J, Balogun W, Fasanmade O, Johnson T, Oli J, Okafor G, Amoah A, Eghan B, Agyenim-Boateng K, Acheampong J, Adebamowo C, Adeyemo A, Rotimi CN. Circulating adiponectin is associated with renal function independent of age and serum lipids in West Africans. International Journal of Nephrology 19. (2012). Doumatey AP, Chen G, Tekola Ayele F, Zhou J, Erdos M, Shriner D, Huang H, Adeleye J, Balogun W, Fasanmade O, Johnson T, Oli J, Okafor G, Amoah A, Eghan BA, Agyenim-Boateng K, Acheampong J, Adebamowo C, Gerry NP, Christman MF, Adeyemo A, Rotimi CN. C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans. Human Molecular Genetics 20. (2012). Tekola Ayele F, Doumatey A, Huang H, Zhou J, Charles B, Erdos M, Adeleye J, Balogun W, Fasanmade O, Johnson T, Oli J, Okafor G, Amoah A, Eghan BA Jr, Agyenim-Boateng K, Acheampong J, Adebamowo CA, Herbert A, Gerry N, Christman M, Chen G, Shriner D, Adeyemo A, Rotimi CN (2012). Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans. Immunogenetics. 21. (2011). Balogun WO, Abbiyesuku FM (2011). Excess renal insufficiency among type 2 diabetic patients with dip-stick positive proteinuria in a tertiary hospital. African Journal of Medicine & Medical Sciences 22. (2011). Balogun WO. Overcoming challenges of glycaemic management in diabetic patients with kidney disease. Tropical Journal of Nephrology. 23. (2006). Balogun WO, Adeleye JO, Akinlade KS, Kuti M, Otegbayo JA. Low prevalence of hepatitis-C viral seropositivity among patients with type-2 diabetes mellitus in a tertiary hospital. Journal of National Medical Association Fellowship Level (1) Pattern of Thyroid Dysfunction and its Metabolic Correlates Among Elderly Patients Attending the Geriatric Centre, University College Hospital, Ibadan – Dr. EKHAIYEME Ejemhen (2022) (2) Serum Cortisol Levels in Patients with Diabetic Foot Ulcers at the University College Hospital, Ibadan, Nigeria - Dr. Emmanuel Chinedu, EGUZOZIE (2023) PREVIOUS STUDENTS Fellowship Level 1. Prevalence of Non-Alcoholic Fatty Liver Disease Among Patients with Type 2 Diabetes Mellitus and its Relationship to Glycaemic Control at UCH, Ibadan - Clement O. Aransiola (2013) 2. Relationship between Thyroid Dysfunction and Pregnancy Outcomes in Women with Gestational Diabetes Mellitus at University of Ilorin Teaching Hospital, Nigeria – Dr. ADIO Mosunmoluwa Obafemi (2018)Profile
Designation: Senior Lecturer
Faculty: CLINICAL SCIENCES
Department: Medicine
Phone Number: +234 8033776720
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Research
Funder: Fogarty/National Institute of Health, USA
Brief Summary: Non-communicable diseases (NCDs) such as diabetes have devastating consequences on African nations such as Nigeria. Most low-resource countries including in Africa are yet to benefit from the fruits of advancement in molecular genetics. Limited access to genetic testing hinders accurate diagnosis of the various forms of diabetes especially maturity onset diabetes of the young (MODY) with consequent mistreatment in Nigeria. Through the application of genetic testing in the clinic, this study is expected to determine for the first time the frequency and genotype variants of MODY in Nigeria as a prototype for other NCDs.
Role: Principal Investigator
Collaborators: Professors: LI Philipson, A. Ogunniyi, Kovler Diabetes Centre, USAPublications
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