Professor John A. OLANIYI

Profile

	Name:  John A. OLANIYI
	Designation: Professor
	Faculty: BASIC CLINICAL SCIENCES
	Department: Haematology
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Biography: Professor J.A. Olaniyi is a Professor of Haematology at the College of Medicine, University of Ibadan and a honorary Consultant Haematologist to the University College Hospital, Ibadan.  He is the current  Head of Department of Haematology. Qualifications include B.Sc(1984) (Hons) Health Sciences)(Obafemi Awolowo University); M.Sc (2007) (Chem. Path) (University of Ibadan); MB.Ch.B (1987) (Obafemi Awolowo University); Member NPMC (1994); FWACP (Lab Med). He started his academic and Professional career as Lecturer 1/consultant Haematologist in the Department of Haematology first at LAUTECH Ogbomoso/Osogbo in June 1998 and in February 2000 crossed to College of Medicine, University of Ibadan as Lecturer 1 and became Professor in October 2016. He collaborated locally, nationally and internationally with many research groups resulting in publication of 90 research articles in reputable journals. He has trained many Resident Doctors and has supervised their Felloship dissertations. He is also an Examiner of West African College of Physician since year 2008 and currently the host examiner. Research Theme: Haematology and Haemato-Oncology. He has published widely. He has about 91 quality publications in renowned international journals(ref google Scholar). His work is supported by some Senate research Grants and collaborations with some research groups.

Resume

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Research

a. Current Research and Capacity Building Projects including Grants

1. A MEMBER OF SPARC-NET_ CESTRA GRANT

Sickle Pan-Africa Research Consortium Nigeria Network consisting of a hub (Tanzania) and collaborative consortium sites in Ghana and Nigeria is one of the major research projects being hosted at the Centre of Excellence for Sickle Cell Disease Research (CESRTA). It is a four year project which started in May 2017. The objectives of SPARCO are: 1. To develop an ethically and legally approved, patient consented, centralized, secure, web-based database of 15,818 paediatric and adult sickle cell patients for health services and research with distribution as follows: 8818 in Nigeria, 4000 in Tanzania and 3000 in Ghana. 2. To develop, implement and evaluate a resource-based, multi-level, “Guidelines for Management of Sickle Cell Disease (SCD) in Sub-Saharan Africa (SSA)”, in order to standardize the care of individuals with SCD. 3. To organize short, medium and long-term training programs to strengthen skills in SCD health services and research. 4.To develop plans for future research by establishing SCD cohorts in SSA in order to create a platform to conduct SCD-related epidemiologic, translational and clinical research.

In line with these objectives, over 1,300 paediatrics and adult sickle cell disease patients across Nigeria have been enrolled so far. SCD research as well as Data management and Genetic counselling organized both within and outside Nigeria.

2. Title: "The Impact of Rituximab On The Treatment Outcome of NHL in Nigeria"
Funder: Roche Pharmaceutical company throuh NSHBT
Brief Summary : Lymphomas are a heterogenous group of neoplasms of the lymphoid tissues traditionally categorized as either Hodgkin’s  Lymphoma (HL) or non-Hodgkin’s Lymphoma (NHL), each displaying distinct behavioural, prognostic and epidemiological characteristics, with varying responses to treatment¹. World Health Organization (WHO) classified lymphomas into three major categories, according to the morphology and immunophynotype, namely B-cell, T- and NK-cell in non-Hodgkin’s lymphoma(NHL) and Hodgkin’s lymphomas(HL).²
AIM AND OBJECTIVES: To review epidemiology and the pattern of treatments offered to patients, treatments outcomes as measured by lymph node regression and survival in months. This is to be compared with the results of previous studies.
METHODOLOGY: Data extraction form will be used to obtain information from the radiotherapy and haematology treatment records and case notes of patients with histological diagnosis of Hodgkin’s lymphoma between 1991 and 2010 at Radiotherapy and Haematology clinics, University College Hospital Ibadan.
DATA ANALYSIS: Data to be obtained will be analyzed using the statistical package for social science (SPSS) version 17.0.
Role: Local Principal Investigator
Collaborators: All Teaching Hospitals in Nigeria

 Completed Research

1. Determination of Haematological Parameters of Patients with Pulmonary tuberculosis

2. Bone marrow abnormalities in patients with Pulmonary Tuberculosis before commencement of therapy

3. Determination of Antioxidant Status, levels of Vitamin E and Essential Trace Elements in Relation to Severity of HIV in Nigerians patients

4. Determination of levels of Cytokines (Interferon gamma, Interleukin 4), levels of Immunoglobulin sub-classes and Anti-oxidant status in Acute Leukaemias cases prospectively recruited at the University College Hospital, Ibadan, Nigeria

5. Determination of Factor VIIIc yield of plasma and cryoprecipitate in different blood groups. Blood group A individuals showed highest yield in plasma and in cryoprecipitate.

6. Tumor Necrosis Factor-alpha (TNF-α), Interleukin-8 and Endothelin-1 Levels in Adult Sickle Cell Anaemia Patients in University College  Hospital, Ibadan, Nigeria

Publications

1. Aken’Ova, Y.A, Bakare, R.A, Okunade, M.A., Olaniyi, J.A (1995) Bacteria causes of acute osteomyelitis in sickle cell anaemia:   Changing infection profile. West African Journal of Medicine, Vol. 14. No. 4,  255-258 

2. Elumelu, T.N., Olaniyi, J.A. Shokunbi, W.A., Campbell, O.B. (2001). Effect of radiotherapy on patients with multiple myeloma in Ibadan, Nigeria. Nigerian Journal of Clinical Practice. Vol. 4. No. 2, 69-71.

3. Olaniyi, J.A., Aken’Ova, Y.A. (2003) Bone marrow findings in patients with pulmonary tuberculosis. African Journal of Medicine and Medical Sciences. Vol. 32. No. 2, 155-157. (Nigeria).

4. Olaniyi, J.A., Aken’Ova, Y.A (2003). Haematological profile of patients with pulmonary tuberculosis at the University College Hospital, Ibadan. African Journal of Medicine and Medical Sciences. Vol. 32. No. 3, 239-242.

5. Oluokun, O.A., Olaniyi, J. A., and Shokunbi W. A (2003). Coagulant factor VIII level among blood donors in Ibadan, Nigeria. Archives of Ibadan Medicine.  Vol. 4.  26-29  

6. Shokunbi, W.A, Olaniyi, J.A. (2005). Therapy related Acute Myeloid Leukaemia 8- years after treatment for Hodgkin’s Lymphoma- A Case Report. Nigerian Journal of        Health and Biomedical Sciences . Vol.4, No. 1, 14-16. .

7. Kehinde, A.O., Olaniyi, J.A., Fakunle, E.E.  (2006). Extra- pulmonary tuberculosis in sickle cell disease: Case report. African Journal of Medicine and Medical Sciences. Vol. 35.  381-384. (Nigeria).

8.  Durosinmi, M.A, Faluyi, J.O., Oyekunle, A.A, Salawu, L, Adediran, I.A,,  Akanmu, S,, Ogbe, O.P., Wakama, T.T., Nwauche, C.A., Enosolease, M.E.,  Halim, D.N.,  Bazuaye, G.N, Okocha, C.E, Olaniyi, J.A., Akingbola, T.S., Mabayoje, V., Raji, A.A, Mamman, A., Kuliya –Gwarzo, A., Ibegbulam, O.G., Ocheni, S, Yohana, T, Arewa, O.P., Bolarinwa, R.A., Kassim, D.O., Ndakotsu, M.A., Amusu, O.A, Akinyanju, O.O. (2008).  The use of imatinib mesylate in Nigerians with chronic myeloid leukaemia.  Cellular Therapy and Transplantation (CTT). Vol. 1: 1-5.

9. Olaniyi, J.A. (2009). An acute Leukaemia masquerading as immune thrombocytopaenic purpura. Clinical Medicine Insights: Case Reports. Libertas Academia. 2; 21-34..  

10. Olaniyi, J.A.,  Arinola, O.G. (2009). Humoral  immunity and haemoglobin F (HbF) in steady state adult Nigerian sickle cell disease patients with asymptomatic malaria. Turkish Journal of Medical Sciences. Vol. 39. No. 6: 953-957.

11. Oluwasola, A.O., Olaniyi J.A., Otegbayo, J.A., Ogun, O.G., Akingbola, T.S., Ukah, C.O,, Akang, E.U., Aken’Ova, Y.A: (2011):  A fifteen year review of lymphomas in a Nigerian tertiary  healthcare centre. Journal of Health Population and Nutrition Vol. 29. No. 4, 1-7. 

12. Olaniyi, J.A., Oluwasola, A.O., Ibijola, I. (2011): Outcome of Therapy of a T-cell Rich B-cell Lymphoma in Ibadan, Nigeria. Mediterranean Journal of Haematology and  Infectious Disease  3: 310-316.

13. Olaniyi, J.A., Akinlade, K.S., Atere, A.D., Arinola, O.G. (2014): Plasma homocysteine, methyl-malonic acid, vitamin B12 and folate levels in adult Nigerian sickle cell anaemia patients. British Journal of Medicine & Medical Research. Vol. 4. No. 6, 1327-1334.

14. Olaniyi, J.A., Alagbe, K.E. (2015):  Spinal cord discitis and pathological lumbar fracture in a sickle cell anaemia patient: A case report. International Journal of Medicine and Medical Sciences Vol. 48. No. 1: 2051-5731

15. Olaniyi, J.A., Ogundeji, P.S., Ogbaro, D.D. (2015):  Immune Thrombocytopaenic Purpura following acute lymphoblastic leukaemia in remission: Journal of Leukaemia http.//dx.doi.org/10.4172/2329-6917.1000180.

16. Olaniyi, J.A., Ige, O.M., Rahamon, S.K., Arinola, O. G. (June 2016): Haematological abnormalities in treatment naïve multi-drug resistant tuberculosis patients with or without Human Immuno-Deficiency Virus (HIV) infection: Arch. Bas. App. Med Vol. 4. No. 1: 57-62.

17. Obiageli E. Nnodu  , Samuel A. Adegoke  , Osita U. Ezenwosu  , Ifeoma I. Emodi  , Ngozi I. Ugwu , Chinatu N. Ohiaeri  , Biobele J. Brown  , John A. Olaniyi  , Hezekiah Isa , Chinedu C. Okeke  , Benard A. Bene , Modupe T. Balogun  , Emmanuel C. Okocha  , John C. Aneke  , Juliana Olufunke J. Lawson 13 , Abjah M. Usman, Ijeoma N. Diaku-Akinwumi , Angela A. Okolo , Yetunde T. Israel-Aina, Mustapha Jamda , Oladapo W. Aworanti  , Frédéric B. Piel , Adekunle D. Adekile :A multicenter survey of acceptability of newborn screening for sickle cell disease in Nigeria. Cureus vol. 10 No  3: e2354. DOI10.7759/cureus.2354

18. Olaniyi JA, Adeoye OA. Plasma cell Leukaemia: a case report and review of literature. (2020). World Journal of Pharmaceutical Research 9(5); 85-93.

19. Aworanti WO. Fasola FA. Kotila TR, Olaniyi JA, Brown BJ (2020). Acute Leukaemia in Sickle cell disease patients in a tertiary health facility in Nigeria: A case series. African Health Sciences 20(3):pg

20. Akinloye, O; Adegbenro, M., Olaniyi, J.A, Rahaman, S.K., Anifowose, A.I., Awosika, E.O., Arinola, O.G. (2011). Interferon-γ, Interleukin 4, Immunoglobulin classes and nitric oxide in Nigerians with acute leukaemia. Sierra Leone Journal of Biomedical Research. Vol .3. No. 3, 138-143.

Chapters in Books

1. Olaniyi J.A:. Megaloblastic Anaemia Chapter 2 in Intech Open Book Title: Current Topics in Anaemia Edited by Jesmine Khan

2. Olaniyi J.A.: Blood Transfusion reactions. Chapter 2in IntechOpen Book Title: Blood Groups, Edited by Anil Tombak

3. Olaniyi J.A. Acute Lymphoblastic Leukaemia. Chapter 6 in Textbook of Medicine In Press

4. Olaniyi J.A: Acute Myeloblastic Leukaemia. Chapter 7. In Essential Textbook of Medicine: Edited by Prof Co Alebiosu and Prof AE Ayodele. Publish bt UNIOSUN Publishin g limited, 2022 ISBN 978-9

5. Olaniyi J.A:. Megaloblastic Anaemia Chapter 2 in Intech Open Book Title: Current Topics in Anaemia Edited by Jesmine Khan

6.  Hypersensitivity reactions.   In  Essential Textbook of Medicine: Edited by Prof Co Alebiosu and Prof AE Ayodele. Publish bt UNIOSUN Publishing limited, 2022 ISBN 978-978-987-399-9.

Supervision

Fellowship

1. Tumor Necrosis Factor-α, Interleukin-8 and Endothelin-1 Levels in Adult Sickle Cell Anaemia  Patients  in  University College Hospital, I badan. Nigeria: DR ADEKUNLE EMMANUEL ALAGBE; MBBS (Ogbomoso)

2. Impact of chemotherapy on antioxidant micronutrient levels in patients with mature lymphoid malignancie: Akunwanta C.U

3. The impact of foetal haemoglobin levels on some inflammatory markers in steady state sickle cell anaemia patients at a Nigerian tertiary health institution: Dr John Akulue; 2016

Grants

Not Available

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Other Interest/Hobbies

I love to worship God

I love listening to music

I love watching football matches

I play chess