Profile
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Name: Michael A. GBADEGESIN |
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Designation: Professor |
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| Faculty: BASIC MEDICAL SCIENCES | |
| Department: Biochemistry | |
| ORCID Profile | |
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Email:This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Biography Micheal A. Gbadegesin Professor M. A. Gbadegesin received his BSc and MSc in Biochemistry, University of Ibadan and his PhD in Molecular Biology, University of Bath, UK. He was promoted to the grade of a Full Professor in Biochemistry, University of Ibadan, Ibadan, effectively 01 October 2017. His doctoral research training was in genomics, and he is currently actively engaged in aspects of toxicology of environmental contaminants and cancer genomics. His interests include molecular hepatotoxicity of environmental contaminants, and understanding of the genomics of chronic, non-communicable diseases such as cancer and diabetes. Prof. Gbadegesin is the recipient/winner of many prestigious scholarships and fellowships such as the Commonwealth Scholarship, UK (2001-2004), Royal Society of Edinburgh Fellowship (2006), Rothamsted International African Fellowship (2008) etc. He took active part in the development of an integrated system-based, community-oriented, and competency-driven curriculum for medical students as a coordinator at pre-clinical level of training. He is a competent teacher of biomedical courses across many academic departments at undergraduate and postgraduate levels. He is actively involved in capacity building and skills impartation through his teaching and research projects supervision. For instances, the following personnel passed through his tutelage: Oluwafemi Alaba (was his MSc student; now a Graduate Teaching Assistant at the University of Maine, US), Opeyemi Soremekun (was his MSc and PhD student; went to do PhD at the University of KwaZulu-Natal, South Africa, and now a Postdoc at MRC/UVRI & LSHTM, Uganda/UK), Olabode Omotoso (employ at African Genomics Company, Inqaba Biotec West Africa Ltd), John Teibo (a PhD student at University of Sao Paulo, Brazil) among others. |
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Research
1. 1994-95 University of Ibadan Senate Research Grant Award(1999)
2. Commonwealth Scholarship, Commonwealth Scholarship Commission, United Kingdom (2001-04)
3. Royal Society of Edinburgh Fellowship, at University of Dundee, UK (2006)
4. Rothamsted International, African Fellowship (2008)
Publications
Selected Publications
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YEAR |
AUTHORS |
TITLE |
JOURNAL |
VOL: Pages |
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2000 |
Gbadegesin MA, OA Odunola and AO Uwaifo |
Protease inhibitor extract of fermented African locust beans (Parkia filicoidea) inhibits aflatoxin B1-induced rat liver glutamyl transferase activity. |
Biokemistri (Nigeria) |
10(2): 93-98. |
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2006 |
Raji Y, FO Awobajo, OT Kunle-Alabi, MA Gbadegesin and AF Bolarinwa |
In vivo and in vitro Reproductive Toxicity Assessment of Ampicillin and Cloxacillin in Mammalian Models. |
International Journal of Pharmacology (Pakistan) |
2(1): 9-14 |
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2006 |
Raji Y, MA Gbadegesin, OA Osonuga, RA Adisa, OS Akinsomisoye, FO Awobajo, OT Kunle-Alabi, PRC Esegbue-Peters, IO Osonuga and AF Lamidi |
Reproductive, Haematologic and Biochemical Profiles of Male Rats Treated with Aqueous Extract of Spondias mombin Bark. |
International Journal of Pharmacology (Pakistan) |
2(1): 126-130. |
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2007 |
Raji Y, OT Kunle-Alabi, S.B. Olaleye, MA Gbadegesin, FO Awobajo, OA Osonuga, AO Odunkanmi, SA Salami and AF Bolarinwa |
Impact of ?-tocopherol on Metronidazole- and Tetracycline-induced alterations in reproductive activities of male Albino Rats. |
Journal of Biological Sciences (Pakistan) |
7(1): 41-46. |
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2007 |
Gbadegesin MA, R Gomez-Vasquez, Reilly K and JR Beeching |
Transcriptionally active Mutator-like transposable element in the genome of cassava (Manihot esculenta Crantz). |
Asian Journal of Plant Sciences (India) |
6(1): 129-136. |
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2007 |
Odunola OA, MA Gbadegesin, SE Owumi and AO Uwaifo |
Petroleum refining chemicals enhance aflatoxin B1-induced toxicities in Wistar rats. |
Journal of Med Science (Bangladesh) |
7(4): 615-619. |
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2008 |
Moyib OK, MA Gbadegesin, OO Aina and OA Odunola |
Genetic variation within a collection of Nigerian accessions of African yam bean (Sphenostylis stenocarpa) revealed by RAPD primers. |
African Journal of Biotechnology (Kenya) |
7(12) 1839 – 1846. |
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2008 |
Odunola OA, E Uka,KA Akinwumi, MA Gbadegesin, OO Osifeso and MD Ibegbu |
Exposure of Laboratory Mice to Domestic Cooking Gas: Implication for Toxicity. |
International Journal of Environmental Research and Public Health (USA) |
5 (3): 172-176. |
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2008 |
Gbadegesin, MA, MA Wills and JR Beeching |
Diversity of LTR-retrotransposons and Enhancer/Suppressor Mutator-like transposons in cassava (Manihot esculenta Crantz). |
Molecular Genetic Genomics (Germany) |
280: 305-17. |
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2009 |
Gbadegesin MA, OA Odunola, KA Akinwumi and OO Osifeso |
Comparative hepatotoxicity and clastogenicity of sodium arsenite and three petroleum products in experimental Swiss Albino Mice: The modulatory effects of Aloe vera gel. |
Food and Chemical Toxicol (England) |
47: 2454-2457. |
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2010 |
Gbadegesin MA and OA Odunola |
Aqueous and ethanolic leaf extracts of Ocimum basilicum (sweet basil) protect against sodium arsenite-induced hepatotoxicity in Wistar rats. |
Nigerian Journal of Physiological Sciences (Nigeria) |
25: 29-36. |
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2010 |
Gbadegesin MA and JR Beeching |
Enhancer/SuppressorMutator (En/Spm)-like transposable elements of cassava (Manihot esculenta Crantz) are transcriptionally inactive. |
Genetic and Molecular Research (Brazil) |
9(2): 639- 650. |
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2011 |
Gbadegesin MA and JR Beeching |
Highly Heterogeneous Ty3/Gypsy-like Retrotransposon Sequences in the Genome of Cassava (Manihot esculenta Crantz). |
African Journal of Biotechnology(Kenya) |
10 (20): 3951-3963 |
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2010 |
Gbadegesin MA and JR Beeching |
Isolation and partial characterisation of root specific promoters for stacking multiple traits into cassava (Manihot esculenta CRANTZ). |
Genetic and Molecular Research (Brazil) |
10(2): 1032-1041 |
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ARTICLES SUBMITTED/ IN PRESS/ACCEPTED: |
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2011 |
Gbadegesin MA and JR Beeching |
Analysis of heterogeneity of Copia-like retrotransposons in the genome of Cassava (Manihot esculenta Crantz) |
Nigerian Journal of Physiological Sciences |
(Accepted) |
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2011 |
Gbadegesin MA, OA Odunola and SE Owumi |
Chemoprotective activity and toxicity of Aloe vera in sodium arsenite treated Swiss Albino Mice. |
Journal of Science Research |
(Accepted) |
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PUBLISHED ABSTRACT: |
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2005 |
Gbadegesin MA, K Reilly and JR Beeching |
Mutator-like transposable element of cassava (Manihot esculenta Crantz) is highly methylated. |
FEBS Journal |
272(s1): 47 |
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2010 |
Owumi SE, OA Odunola, MA Gbadegesin, KL Nulah, A Mohammed, CO Oloye, AC Oloidi, MO Obadare and OO Oladeji |
Chemoprotective properties of some African spices on sodium arsenite-induced toxicities in albino Wistar rats. |
Cancer Prevention Research |
3(12): B61 |
Supervision
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Grant
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