Dr. Adejumoke I. AYEDE

Basic Information

	Name: Dr. Adejumoke I. AYEDE	Faculty: CLINICAL SCIENCES
	Email: This email address is being protected from spambots. You need JavaScript enabled to view it.	Department:Paediatrics
	Designation: Reader
Brief Biography:

Resume

1. Name:                   Adejumoke I. AYEDE

          Department:          Paediatrics

          Faculty:                 Clinical Sciences

          College:                 College of Medicine

II         (a)      First Academic Appointment:         Associate lecturer (1 August 2004)

          (b)      Present Post:                                   Lecturer 1 (22 September 2006)

          (c)      Date of last Promotion:                   Not applicable

          (d)      Date last considered                       Not applicable 

III        University Education (with Dates):

a)        University of Ibadan, Ibadan, Nigeria             1986 – 1992

b)        University of Ibadan, Ibadan, Nigeria              2003- 2004

IV         Academic Qualifications with Dates and Granting bodies:

  a)   Bachelor of Medicine, Bachelor of Surgery University of Ibadan   Aug  1992 

  b)   Sc. Epidemiology, University of Ibadan, Ibadan                          July 2004

V          Professional Qualifications (with Dates):

FMCPaed, November 2002    (National Postgraduate Medical College of Nigeria) 

VI         Scholarships, Fellowships and Prize:

• Best Senior ResidentYear 2002, Department of Paediatrics, University College Hospital, Ibadan. 
• Best M.Sc. Student, 2004: Department of Epidemiology, Medical Statistics and Environmental Health, Faculty of Public Health, College of  Medicine, University of Ibadan, Ibadan.

VII       Honours, Distinctions and Membership of Learned Societies:

• Member, Nigerian Medical Association
• Member, Nigerian Medical Women Association
• Member, Paediatric Association of Nigeria
• Member, ,Nigerian Society for  Paediatric Infectious Diseases
• Member Nigerian Society of Neonatal Medicine
• Member, Nigerian Institute of Management
• Member, Medical and Dental Consultants of Nigeria 

VIII      Details of Teaching Experience at the University Level:

• Teaching:

       Lectures to undergraduate medical students:

       I have given regular core lectures to undergraduate medical students as a faculty staff since 2006 covering the following subjects: Neonatology: Haematological disorders in the newborn (including reference values for newborn, physiologic anaemia, anaemia of prematurity, acute and chronic anaemia, polycythaemia in the newborn, haemorrhagic disease of the newborn, consumptive coagulopathy, transient idiopathic thrombocytopenic purpura and neonatal thrombocytopenia) Neonatal infections (including neonatal sepsis, superficial infections, deep infections, chronic infections and cutaneous infections)

         Infant nutrition:

• This includes: role of nutrition in growth and development, determinant of  feeding practices, daily nutritional requirement, breast feeding and its benefits, challenges of breast feeding, breast  feeding problems, contraindications to breast feeding, composition of human breast milk, differences between cow milk and human milk,  positioning and attachment, complementary feeds,feeding disorders such as constipation, regurgitation, vomiting and diarrhoea in the newborn

Childhood morbidity and mortality:

• Topics covered include:definitions of morbidity and mortality terms, global perspective of under- five mortality, sources of morbidity and mortality data, trends in childhood morbidity and mortality, factors predisposing to under-5 mortality, peculiarities of under-5 mortality in Nigeria, health causes of under -5 mortality in Nigeria, determinant of mortality patterns and strategies for the reduction of under five mortality in Nigeria.
• Other topics are: concept of mother, newborn and child continuum of care, rationale for the continuum of care, elements of continuum of care, essential newborn care interventions, tackling malnutrition in children, integrated management of childhood illnesses, increasing immunization coverage of mothers and babies and the global immunization vision and strategy.

Protein energy malnutrition:

• The topics taught include: overview of protein energy malnutrition (PEM), clinical assessment of PEM, major micro and macronutrients, assessment of nutritional status, anthropometry, laboratory assessment ofnutritional deficiency, use of dietary assessment, epidemiology of PEM, aetiology and predisposing factors of PEM, PEM classification, pathophysiology, features, complications, treatment and prognosis of PEM.
• Seminars:

       Social Paediatrics:

• Home visit seminars. I take turns with other lecturers in the department in presiding over this seminar to focus on the relationships between socio-economic and environmental factors and childhood diseases.
• Clinical teachings:

      Bedside teaching and tutorials:

• Clinical examination of the newborn
• The physical signs of maturity in the newborn
• The preterm neonate
• Neonatal jaundice
• Respiratory problems in the newborn
• The asphyxiated baby
• Essential newborn care
• Metabolic disorders in the newborn
• Clinical demonstrations during the weekly neonatology, the high   risk neonate   and general paediatric clinics:
• At these weekly clinics, illustrative cases are demonstrated and taught to medical students. The students take turns to clerk and examine such patients and make clinical presentations which form the basis of the clinical teachings that then follow.
• I take turns with other lecturers in the department to examine indept (as the lead discussant) at the weekly grand rounds, selected subjects, in order to demonstrate the interplay between academic and clinical considerations for the benefit of undergraduate and postgraduate students.   

Internal Examiner:

• I have been involved in the conduct of part IV MBBS university examinations since 2006.
• Lectures to and supervision of post graduate students research projects:

Post graduate training in paediatrics:

• I take turns in rotation with other lecturers in the department to give lectures to postgraduate doctors covering subjects in general paediatrics and neonatology. I teach these subjects also at twice weekly ward rounds.

Postgraduate training in child health:

• I was involved in the training of postgraduate students in Institute of Child Health from 2004 to 2006. These were postgraduate students for Diploma in Paediatrics and MPH Child and 
   Adolescent Health. Topics covered include Newborn Screening and Statistical Methods in Epidemiology.

Postgraduate training in Epidemiology, Medical Statistics and Environmental Health (EMSEH) since 2004 as an Associate Lecturer and 2006 as a Joint Lecturer

• Teaching of postgraduate students in the Department of   Epidemiology,  Medical Statistics and Environmental Health
• Topics covered include: practical calculations in statistical methods, nutrition and health indices, child survival and population dynamics.
• Practical epidemiology and paediatrics field training for postgraduatestudents in EMSEH.

Supervision of postgraduate theses:

I have supervised and co-supervised the following postgraduate theses:

• Onifade Sunday Oluwaseun in Institute of Child Health, College of Medicine, Ibadan. 2005. Neonatal disease presentations at Oni Memorial Children’s Hospital, Ibadan: A three year review.
• AbafeAkpojevwe Ovokeroye in Department of Chemistry, University of  Ibadan. 2010. Development of simple and rapid methods for the routine analysis of antimalarial drug (Artesunate, Artemether-Lumenfantrine, Amodiquine and Sulfadoxine- Pyrimethamine) metabolites in biological fluids of infants and pregnant women in Nigeria.
• Folarin Taiwo Bukola in Department of EMSEH, College of Medicine, University of Ibadan. Ongoing. Hygiene and sanitation risk factors for diarrhoea in children under -5 in two selected hospitals in Ibadan.
• Onipede Olumuyiwa Joshua in Department of Chemistry, University of Ibadan. Ongoing. Determination of some phthalate esters and their metabolites in blood,urine and breast milk samples obtained from volunteer at the University College Hospital, Ibadan. 
• Agboluaje Nafisat O in the Department of EMSEH, College of Medicine, University of Ibadan. On going. Housing conditions and perceived health effect among under-5 children in Omi Adio 
   community.

Researches

1. Completed

(1)    Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine-pyrimethamine in the management of moderately severe malaria in Nigerian children.

(2)    Trends in clinical autopsy rate in a Nigerian tertiary hospital.

(3)    Community-directed interventions for priority health problems in Africa: A multicountry study. 

(4)    Cytokine profiles and antibody responses to Plasmodium falciparum malaria  infection in individuals living in Ibadan. 

(5)    Retinoblastoma: The challenges of management in Ibadan.

(6)    Cellular response to modified plasmodium falciparum MSP 1-19. Antigens  in  individuals previously exposed to natural malaria infection.

(7)     An open randomized  controlled trial in comparing two artesunate-based combination treatments artesunate/sulfamethoxy-pyrazine/ pyrimethamine (FDC over 24 hours) and artesunate/amodiaquine (FDC over 48 hours)] on Plasmodium falciparum malaria in Nigerian children. 

(8)     Development and validation of a thin layerchromatographic method for the simultaneous determination of sulphadoxine-pyrimethamine, artemether-lumenfantrine,its metabolites and artesunate+amodiaquine metabolites in human urine.

(9)     The role of routine post-natal abdominal ultrasound for newborns in a resource-poor setting: a longitudinal study. 

(10)       Pattern and indications of neonatal blood transfusion in Ibadan.

(11)       Development and validation of a thin layer chromatographic method for the determination of Artesunate and Amodiaquine in tablet formulation. 

(12)       Neonatal hepatobiliary response to oral feeds as visualised by abdominal ultrasonography.

(13)       Neonatal splenic normogram in relation to weight, age and length.

(14)       Management of neonatal jaundice at home and peripheral health facilities: a community based study.

(15)       Routine neonatal multi- drugs usage and its potential implications: a community based study. 

(16)       Early initiation of breastfeeding and its determinants: a community based study. 

(17)       Malaria anaemia and risk factors in infants.

(18)       Home management of ear infections in children: a community basedstudy. 

(19)       Implicated genetic markers in the predilection for different forms of malaria in Nigerian children

(20)       Immunocytochemistry of severe malaria in Nigerian children

1. In progress

          (1)  Kidney normogram in Nigerian newborn (Mac Arthur founded). This was started two years ago and we have recruited over three hundred newborns. The study will help to develop a kidney normogram for Nigerian newborns. Hopefully, it will be completed by the end of this year. Part of the research findings has been published in BMC Paediatrics.

           (2)   Multi centre Clinical trial on simplified antibiotic regimen for the community treatment of neonatal sepsis.(WHO/ Bill & Melinda Gate foundation: Principal Investigator). The study will provide the information on the most effective simplified antibiotics and combination therapy that can be used for the management of neonatal sepsis at primary health care level and home. It was commenced on the first of December 2010 has reached completion. Part of the work is being written up for publication.

            (3)  The study on the survival trends in children with different severity pneumonia was started in February 2012 months ago and is meant to be for a period of two years.

Publications

a)Articles that have already appeared in learned journals

1. Sowunmi, A., Falade, A.G., Adedeji, A.A., Ayede,I.,Fateye, B.A., Sowunmi, C.O.  &  c Oduola, A.M J. (2001). Comparative plasmodium falciparum kinetics during treatment  with amodiaquine and chloroquine. Clinical Drug InvestigationVol. 21,371- 381.  
2. Sowunmi, A., Ayede,I.,Falade, A.G., Ndikum, V.N., Sowunmi, C.O., Adedeji, A.A., Falade, C.O., Happi, T.C.  & Oduola, A.M. J. (2001). Randomized comparison   of chloroquine and amodiaquine in the treatment of acute, uncomplicated, plasmodium falciparum malaria in children. Annals of Tropical Medicine &  ParasitologyVol. 95, 549-558.  
3. Falade,C.O., Fadero,F.F. , Happi, C. T. , Dada-Adegbola,H.O., Gbotosho,G.O., Ayede,A.I., Falade,A.G., 0duola,A.M.J.& Salako,L.A.(2007).  Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine- pyrimethamine  in the management of moderately severe malaria in Nigerian   children. American   Journal of Tropical Medicine & Hygiene Vol.76, 1–6.
4. Oluwasola, A. O., Fawole, O.I., Otegbayo, J.A., Ayede, I. A., Ogun, O.G., Okah,  C. O. & Bamgboye, A.E. (2007).Trends in clinical autopsy rate in a  Nigerian  tertiary hospital. African Journal of Medicine & medical Sciences Vol. 36, 267-272
5. Community-directed interventions for priority health problems in Africa: results of  a multicountry study. Bulletin of the World Health Organization;  Research Article DOI:  10.2471/BLT.09.069203.The CDI Study Group: The CDI Study Group that authored this paper is composed of the following members (with countries listed in alphabetical order): Burkina Faso: U Amazigo (WHO/APOC, Ouagadougou), T Diarra (WHO/AFRO, Ouagadougou); Cameroon: S Wanji , P Enyong , N Tendongfor , Z Njoumemi, C Nana, LV Moukam, YT Longang, T Njie, F Datchoua, I Molioum, LK Abia (University of Buea); I Takougang, JP Wabo, TM Darios, N Henriette, LN Ndeffo, F Innocent, JJ Keuzeta, D Medard, P Tatah (University of Yaoundé I); Kenya: M Amayunzu (African Institue for Health and Development, Nairobi); Nigeria: O  Oladepo, F Oshiname, A Ajuwon, A Jaiyeoba, O Alaba, K Olayinwola, S Otusanya, 
   A Oyeyemi, M Titloye, JD Adeniyi, OS Arulogun, D Soyibo, OA Lawanson, BA  Adeniyi, CP Babalola, TTA Elemile, OS Ndekwu, JA Oso, L Andah, AI Aiyede, N  Afolabi, OO Kale (University of Ibadan); E ElHassan, S Isyaku, S Sanda, FNC 
    Enwezor, O Adekeye, F Agbo, MK Ogungbemi, D Lawong, F Folurunsho, F Ibrahim, A Gwom (Sight Savers International, Kaduna); O Akogun, JA Badaki, DO Echeta, AO Adesina, S Njobdi, J Manabete, K Shitta, U Ahmed (University of Yola), J Okeibunor (University of Nigeria, Nsukka); Sudan: M Homeida (Academy of Medical Sciences and Technology, Khartoum); Uganda: R Ndyomugyenyi, AT Kabali, B Kiberu, Z Mugaba (Ministry of Health, Kampala); Switzerland: J Sommerfeld, JHF Remme (retired) (WHO/TDR, Geneva); United States of America: W Brieger (John Hopkins Bloomberg School of Public Health, Baltimore), S Zimicki (Academy for Educational Development, Washington, DC).
6. Iriemenam, N. C. , Okafor, C. M. F., Balogun, H. A., Ayede,A.I., Omosun,Y.,  Persson, J., Hagstedt, M., Anumudu, C. I., Nwuba, R. I., Troye-Balomberg, M. & Berzins,    K.(2009). Cytokine profiles and antibody responses  to Plasmodium falciparum    malaria infection in individuals living in Ibadan southwest Nigeria. African Health   Sciences Vol. 9, 66-74            
7. Bekibele, C. O. , Ayede,A. I. ,Asaolu, O.O. & Brown, B. J. (2009).  Retinoblastoma: The challenges of management in Ibadan, Nigeria. Journal of Pediatric Hematology      & Oncology  Vol. 31, 552-555.   
8. Okafor, C.M.F., Omosun,Y., Anumudu, C.I., Nwuba, R.I., Ayede,I. , Awobode, H.O.   Langhorne, J., Holder, A. A., Uthaipibw, C., Odaibo, A.B.  & Troye-Blomberg, M.  (2009). Cellular response to modified plasmodium falciparum MSP 1-19. Antigens in    individuals previously exposed to natural malaria infection. MalariaJournal  Vol. 8: 263doi:10.1186/1475-2875-8-263.
9. Ayede A.I., Falade A.G., Sowunmi A. & Jansen H. (2010). An open randomized controlled trial in  comparing two artesunate-based combination treatments artesunate/ sulfamethoxy-pyrazine/ pyrimethamine (FDC over 24 hours) and a  rtesunate/amodiaquine (FDC over 48 hours)] on Plasmodium falciparum malaria in Nigerian children. Malaria Journal  9:378doi:10.1186/1475-2875-9-378
10. Ayede A.I, Adewuyi G.O. & Abafe A.O.(2011).Development and validation of a thin layerchromatographic method for the simultaneous determination of sulphadoxine-pyrimethamine, artemether- lumenfantrine its metabolite and artesunate+amodiaquine metabolites in human urine.   International Journal of Chemistry VOL 21 (1), 41 – 53.
11.  Agunloye A.M, Ayede A. I. & Omokhodion S.I. (2011).The Role of Routine Post-natal abdominal ultrasound for newborns in a resource-poor setting : a longitudinal study. BMC Paediatrics, 11: 64 doi: 10.1186/1471-2431-11-16
12. Ayede A.I. (2011) Achieving optimal feeds for preterm babies, recommendations and  realities  in  practice: Nigerian perspective. Annals of Ibadan Postgraduate vol.9 no 1, 1-7
13. Ayede A. I. & Akingbola T.S( 2011).  Pattern, complication and review of Neonatal Blood  transfusion in Ibadan, southwest  Nigeria.  Annals of Ibadan Postgraduate Medicine. vol.9 no 1,30-36
14.  Otegbayo J. A.  Ayede A. I,  Ogunbiyi J.O.  Accuracy of clinical diagnosis of liver diseases at Ibadan. West African Journal of  Medicine. Accepted for publication July 2011
15. Falade A.G & Ayede A.I(2012).Epidemiology, aetiology and  management of childhood acute community-acquired pneumonia in developing countries. Afr. J. Med. Sci 40, 293-308.
16. Adewuyi G.O.  Ab afe A.O & Ayede A. I. (2012). Development and validation of 
    a thin layerchromatographic method for the determination of Artesunate and  Amodiaquine in tablet formuilations.  African journal of Biotechnology Vol 10(60),  PP 13028-1303.
17. Fatiregun, SA Olowookere, EE Isere, AI Ayede (2012).  Epidemiology of an outbreak of cholera in a south-west state of Nigeria. Afr J Epidemiol Infect ; 27(4):201-204.
18. Ayede A.I. (2012). Persistent mission home delivery in Ibadan: attractive role of  traditional birth attendants.  Annals of Ibadan Postgraduate Medicine vol 10 No. 22-27

XIII. Major Conferences attended with Papers read in the last five years:

• ·WHO/TDR/JBI Workshop on quantitative and qualitative evidence based research. Pretoria South Africa.Sept. 2007       

• ·40thPaediatric Association of Nigerian International Conference, Ibadan.  Jan 2009

• ·Sickle cell disease and thalasaemia course, St. Thomas Hospital London October 2009

• ·Annual Conference of American Society of Tropical Medicine and Hygiene, Washington DC, USA .November 2009An open randomized  controlled trial in comparing two artesunate-based combination treatments artesunate/ sulfamethoxy-pyrazine/ pyrimethamine (FDC over 24 hours) and artesunate/amodiaquine (FDC over 48 hours)] on Plasmodium falciparum malaria in Nigerian children.
• ·International Conference on Feeding the Toddler: Challenges. Prague, Czech Republic March 2011

• ·African/Middle East Summit on Pneumococcal Disease in children, Dubai April 2011.

• ·Annual Neonatal Conference, Durham UK, June, 2011

• ·Paediatrics Association of Nigerian Conference2012, Ife, Nigeria: Presented:  The Role of Routine Post-natal abdominal ultrasound for newborns in a resource-poor setting: a longitudinal study.

• ·African Vaccinology Conference, Cape Town, South Africa, November 2012.

• ·Paediatrics Association of Nigerian Conference, Enugu, 2013.

Contact Information

Phone: 08033740698	Address:	Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
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