Dr. Adekunle A. ONIFADE

Basic Information

 Akinlosotu

Name: Dr. Adekunle A. ONIFADE

 Faculty: BASIC CLINICAL SCIENCES

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

  Department:Chemical Pathology/Immunology

 Designation: Senior Lecturer

 Brief Biography:

Resume

CURRICULUM VITAE
I

  1. Name:                                            Adekunle   A.   Onifade  
  2. Date of Birth:                                12 November, 1974
  3. Department:                                  Chemical Pathology
  4. Faculty:                                          Basic Medical Sciences

II.

  1. First Academic Appointment:      Lecturer II
  2. Present Post (with date):               Lecturer I (01 October, 2015)
  3. Date of Last Promotion:               01 October, 2015
  4. Date Last Considered (in cases where promotion was not through): Not applicable

III. University Education (with dates)

  1. University of Ilorin 1994 - 2001
  2. University of East London 2007 - 2008
  3. Kingston University, London 2008 - 2011

IV. Academic Qualifications (with dates and granting bodies)

  1. M.B.Ch.B. (Bachelor of Medicine, Bachelor of Surgery )
    University of Ilorin 2001
  2. M.Sc. (Biomedical Immunology )
    University of East London 2009
  3. Ph. D. (Immunology )
    Kingston University, London 2011

V. Professional Qualifications and Diplomas (with dates): Nil

VI. Scholarships, Fellowships and Prizes (with dates) in respect of Undergraduate and Postgraduate work only): Nil

VII. Honours, Distinctions and Membership of Learned Society:

  1. Nigeria Medical Association (NMA) 2002
  2. British Society of Immunology (Full member) 2010

VIII. Details of Teaching/Work Experience:

  1. Undergraduate:
    1. I teach MBBS/BDS students Immunology section of Chemical Pathology Courses (Theory and Practical)
    2. I also teach BMLS students Immunology related courses
  2. Postgraduate:
    1. CPY 703- Chemical Pathology Laboratory Methods
    2. CPY 701- Introductory Chemical Pathology
    3. CPY 732- Immunology Laboratory Methods
    4. EMS 702- Introduction to Basic Medical Science
    5. CPY 705- Chemical Pathology Seminars
    6. CPY 731- Immunology
    7. I supervise MSc students in projects (CPY 741): Completed MSc projects -9 On-going –Nil
    8. Course coordinator CPY 731, 732, EMS 702
  3. Administrative Duties:
    1. Postgraduate Examination Officer 2013-2015
    2. Postgraduate Coordinator 2015-2016
    3. Departmental Representative at Faculty Board Meeting and Postgraduate School Board Meeting 2018
  4. Community Service:
    1. Review of journal articles
    2. Interpretation of results obtained from immunological analysis. Such results are used for diagnosis, prognosis, monitoring and treatment
    3. Training of resident doctors (Registrars) on 2-week rotation to Immunology unit of Chemical Pathology

Collaborative supervision of postgraduate students and resident doctors from UCH and other teaching hospitals

Researches

  1. Completed Research
    1. Immunological markers in diagnosis and monitoring of HIV and tuberculosis infection
    2. Antimicrobial peptides (psoriasin) in Nigerian hands and effectiveness of hand washing and drying in infection control
    3. Safety (acute and chronic) profiles and effectiveness of herbal preparation for HIV infection
    4. Role of malaria, anaemia and immune response in paediatric patients
    5. Inflammatory potentials of medicinal plants and their products
  2. Research In Progress
    1. Role of cytokines in HIV progression

HIV monitoring with CD4 count and viral load are associated with problems thus need for less expensive, accessible and reliable methods of determining response to treatment. Selected cytokines produced by CD4 T cells were measured in HIV patients at periodic interval. About 70% of the cytokines have been successfully assayed with CD4 count and viral loads

    1. Chemokine ligands concentration in HIV patients

Susceptibility of individual to HIV infection had been a major concern necessitating R4 and R5 ligands measurements in healthy, discordant and concordant couples. We have successfully determined the concentrations of these chemokine ligands in healthy, concordant and discordant couples however their concentrations at different phases of therapy had not been measured

    1. Role of diagnostic markers in Hepatitis B infection

Specificity and sensitivity had been a challenge in Hepatitis B diagnosis. Conventional liver functions test and antibodies to Hepatitis B surface, envelope and core antigens are to be assayed. Their levels will be compared with viral load. Viral load has not been done awaiting reagents and other logistics

  1. Project, Dissertation and Thesis
    1. Effectiveness of different hand washing and drying agents on hand flora

Are herbal remedies effective in HIV infection in Nigeria?

Publications

  1. Books already published: Nil
  2. Chapters in books already published:
    1. Onifade, A.A., Oladeinde, B.H. and Mokogwu, T. (2012). Recent advances In Novel Drug Carrier Systems Ali Demir Sezer (Ed). Recent advances In Novel Drug Carrier Systems London: Intechopen Press, pp 471-482, ISBN: 978-953-51-0810 (United Kingdom) (Contribution: 70%)
    2. Rahamon, S.K., Onifade, A.A., and Arinola, O.G. (2017). HIV/aIDS Oxidative Stress and Dietary antioxidants (Ed). HIV/AIDS Oxidative Stress and Dietary antioxidants Munich: Academic Press, pp 51-61, ISBN: 9780128098547 (Germany) (Contribution: 60%)
  3. Articles that have already appeared in Refereed Conference Proceeding: Nil
  4. Patents: Nil
  5. Articles that have already appeared in learned journals:
    1. Onifade, A.A., Jewell, A.P. and Okesina, A.B. (2010). Preliminary investigations of are herbal remedies effective in HIV infection in Nigeria, Tropical Journal of Health Sciences Vol. 17.2. pp 51-55 (Nigeria) (Contribution: 70%)
    2. Ajeigbe, K. O. , Ndaman, Z. A. , Amegor, O. F. , Onifade, A.A., Asuk, A. A. , Ibironke, G.F. and Olaleye, S.B. (2011). Anti-nociceptive and anti-inflammatory potential of coconut water (Cocus nucifera L.) in rats and mice, Australian Journal of Basic and applied Sciences Vol. 5.9. pp 1116-1122 (Australia) (Contribution: 20%)
    3. Onifade, A.A., Jewell, A.P. , Okesina, A.B. , Ojezele, M. , Nwanze, J.C. , Saka, G. , Yong, K. , Adejumo, B.A. , Igbe, A.P. and Egunjobi, A.O. (2011). The Phytochemistry and Safety of ?-zam, herbal remedy A-Zam used for treatment of HIV infection in Nigeria, Tropical Journal of Health Sciences Vol. 18.1. pp 40-45 (Nigeria) (Contribution: 50%)
    4. Onifade, A.A., Jewell, A.P. and Okesina, A.B. (2011). Virologic and immunologic outcome of treatment of HIV infection with herbal concotion, A-zam among clients seeking herbal remedy in Nigeria, African Journal of Traditional, Complementary and alternative Medicine Vol. 8.1. pp 37-44 (Nigeria ) (Contribution: 70%)
    5. Onifade, A.A., Jewell, A.P. , Okesina, A.B. , Yong, K. , Ojezele, M. , Nwanze, J.C. , Saka, G.O. , Sule, W.F. , Aladekamika, S.T. and Ajao, A. (2011). Effect of combination therapy of HAART and A –Zam herbal preparation for HIV infection in rats, Journal of aIDS and HIV Research Vol. 3.2. pp 38-42 (United Kingdom) (Contribution: 50%)
    6. Adejumo, B.I., Dimka, U. , Ewenighi, C.O. , Onifade, A.A. , Mokogwu, A.T. , Erhabor, T.A. Ukatu, E. and Nnatuanya, I.N. (2012). Incidence and risk of anaemia in type-2 diabetic patients in the absence of renal impairment, Health Vol. 4.6. pp 304-308 (China) (Contribution: 30%)
    7. Oladeinde, B.H., Omoregie, R. , Osakue, E.O. and Onifade, A.A. (2012). Evaluation of laboratory request forms for incomplete data at a rural tertiary hospital in Nigeria, New Zealand Journal Medical Laboratory Sciences Vol. 66.1. pp 39-41 (New Zealand) (Contribution: 30%)
    8. Oladeinde, B.H., Omoregie R. , Olley M. , Anunibe, J.A. , Onifade, A.A. , and Oladeinde, O.B. (2012). Malaria and Anemia among Children in a Low Resource Setting In Nigeria, Iranian Journal of Parasitology Vol. 7.3. pp 31-37 (Iran) (Contribution: 30%)
    9. Oladeinde, B.H., Omoregie, R. , Olley, M. , Anunibe, J. A. and Onifade, A.A. (2013). A 5-year surveillance of wound infections at a rural tertiary hospital in Nigeria, African Health Sciences Vol. 13.2. pp 351-356 (Uganda) (Contribution: 25%)
    10. Onifade, A.A. (2014). Is the antimicrobial peptide (psoriasin) absent in palms of Nigerian residents?, Archives of Basic and applied Medicine Vol. 2.1. pp 55-58 (Nigeria) (Contribution: 100%)
    11. Onifade, A.A., Ajeigbe, K.O. , Omotosho, I.O. , Rahamon, S.K and Oladeinde, B.H. (2013). Attitude of HIV patients to herbal remedy for HIV infection in Nigeria, Nigerian Journal of Physiological Sciences Vol. 28.0. pp 109-112 (Nigeria) (Contribution: %)
    12. Ajeigbe, K.O., Onifade, A.A. , Omotoso, D.R. , Enitan, S.S. and Olaleye, S.B. (2014). Anti-ulcerogenic activity of Aspilia Africana leaf extract: Roles of gastric acid oxidative stress and neutrophil infilteration, Africa Journal of Biomedical Research Vol. 19.2. pp 193-201 (Nigeria) (Contribution: 40%)
    13. Okoli, S.U., Charles-davies, M.A., Onifade, A.A. , and Adekola, S. (2015). Hypogonadism in Males Exposed To Mixed Chemicals in a Mechanic Village in Bodija, Ibadan, Journal of Scientific Research and Reports Vol. 8.7. pp 1-9 (Italy ) (Contribution: 30%)
    14. Adekola, S.A., Charles-Davies, M.A., Onifade, A.A. , and Okoli, S.U. (2015). Oxidative Stress Biomarkers and their Relationship with Testosterone in Male Automechanics in Ibadan, Nigeria, British Journal of Medicine & Medical Research Vol. 12.9. pp 1-11 (Italy) (Contribution: 30%)
    15. Ojezele, M.O., Abatan, M.O. and Onifade, A.A. (2015). Phytochemistry, phenolic contents and free radical scavenging of Bauhinia thoningii Kurtz and Ricinus communis L extracts as possible contribution to medicinal effects, British Journal of Pharmaceutical Research Vol. 7.1. pp 9-15 (United Kingdom) (Contribution: 50%)
    16. Ude, A.N., Edem, V.F., Onifade, A.A., and Arinola, O.G. (2016). Serum Levels of Selected Vitamins and Trace Elements in Nigerian Consumers of Alcoholic Beverage: A Suggestion for DNA Hypomethylation, Nigerian Journal of Physiological Sciences Vol. 31.1. pp 101-104 (Nigeria) (Contribution: 40%)
    17. Omotosho, I.O., Adeoti, A.T., Adeoye, A.M. and Onifade, A.A. (2016). ). Iron Overload decreases IL10 and TNF- ? and increases IL5 and TGF in Nigerian Hypertensives., Toxicology Digest Vol. 1.1. pp 58-67 (Nigeria) (Contribution: %)
    18. Onifade, A.A., Emeka, G.J., Olaniyi, J.A. , Adeyanju, A.S. , Ojerinde, A.O. and Aiku, A.O. (2016). Non-reliability of Beta-2 Microglobulin and Neopterin as Immunological Markers of HIV Infection, Africa Journal of Biomedical Research Vol. 19.3. pp 205-212 (Nigeria) (Contribution: 50%)
    19. Onifade, A.A., Ojerinde, A.O., Emeka, G.J. , Agbedana, E.O. and Oluogun, W.A. (2017). The role of IgG, IgA and IgM as immunological markers of HIV/AIDS progression, Journal of AIDS and HIV Research Vol. 9.7. pp 152-158 (United Kingdom) (Contribution: 50%)
    20. Oyero, O.G., Onifade, A.A. , and Baba, M. (2017). Immunomodulatory Potential of Herbal Formulations Containing Seeds of Nigella sativa Linn, Africa Journal of Biomedical Research Vol. 20.1. pp 217-221 (Nigeria) (Contribution: 60%)
    21. Onifade, A.A. , Edem, V.F. and Arinola, O.G. (2018). Serum and sputum surfactants -A and -D in multidrug-resistant and drug sensitive tuberculosis patients, African Journal of Clinical and Experimental Microbiology Vol. 19.2. pp 88-92 (Nigeria) (Contribution: 70%)
    22. Onifade, A.A., Edem, V.F. , Ige, O.M. and Arinola, O.G (2018). TNF-alpha Levels in Serum and Mononuclear Cell Lysate of Nigerian Tuberculosis Patients at Diagnosis, Medical Journal of Zambia Vol. 45.1. pp 1-5 (Zambia) (Contribution: 60%)
    23. Onifade, A.A. , Edem, V.F. and Arinola, O.G. (2018). Levels of Interleukin-6 In Mononuclear Cell Lysate of Nigerian Pulmonary Tuberculosis Patients, Tropical Journal of Health Sciences Vol. 25.3. pp 46-50 (Nigeria) (Contribution: 70%)
  1. Books,Chapters in Books and Articles accepted for Publication: Nil
  2. Technical Papers and Monographs: Nil

XI. Major Conferences Attended with Papers Read (in the last 5 years):

  1. Ibadan 2014, Physiology Department, University of Ibadan, Ibadan, Nigeria . 12-14th February 2014.
  2. UCBR 2014, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria . 5-9 July 2014.

    Paper Read: an assessment of the Modulatory Effect of Zinc on Humoral Immune Parameters In Welders and Cement Block Moulders In Ogbomosho, Nigeria
  3. Osogbo 2015, West african Network of Natural Products Research Scientists, Osogbo, Nigeria . 10-14 July 2015.

    Paper Read: Nigella Sativa and HaaRT Potentially Cured HIV Infection
  4. Rome 2015, Antiviral Research society, Rome, Italy.11-15 July 2015.

    Paper Read: Efficacy of alpha-zam In the therapy of HIV Infection among Individuals Seeking alternative Treatment In Nigeria
  5. 5th UCBR, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria . 12-15th July 2016.

    Paper Read: Clinical Utility of CD4+ve T Cells and Immunoglobulin Levels In the Management of HIV/aIDS Patients In Nigeria
  6. 4th International Scientific Conference, Nigerian Institute of Medical Research, Lagos, Nigeria. 7-9th November 2017.
  7. 6th UCBR, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria . 10-14 July 2018.

    Paper Read: Plasma Levels of Interleukin 1 and 6 In Human Immunodeficiency Virus and Malaria Positive Patients

    Paper Read: Estimation of Immunological and Biochemical Parameters In Hepatitis B Positive Patients

XII. Ten Best Publications that Reflect the Totality of my Contributions to Scholarship:

  1. Onifade, A.A., Jewell, A.P. and Okesina, A.B. (2010). Preliminary investigations of are herbal remedies effective in HIV infection in Nigeria, Tropical Journal of Health Sciences Vol. 17.2. pp 51-55 (Nigeria) (Contribution: 70%)
  2. Onifade, A.A., Jewell, A.P. and Okesina, A.B. (2011). Virologic and immunologic outcome of treatment of HIV infection with herbal concotion, A-zam among clients seeking herbal remedy in Nigeria, African Journal of Traditional, Complementary and alternative Medicine Vol. 8.1. pp 37-44 (Nigeria) (Contribution: 70%)
  3. Onifade, A.A., Jewell, A.P. , Okesina, A.B. , Ojezele, M. , Nwanze, J.C. , Saka, G. , Yong, K. , Adejumo, B.A. , Igbe, A.P. and Egunjobi, A.O. (2011). The Phytochemistry and Safety of ?-zam, herbal remedy A-Zam used for treatment of HIV infection in Nigeria, Tropical Journal of Health Sciences Vol. 18.1. pp 40-45 (Nigeria) (Contribution: 50%)
  4. Onifade, A.A. (2014). Is the antimicrobial peptide (psoriasin) absent in palms of Nigerian residents?, Archives of Basic and applied Medicine Vol. 2.1. pp 55-58 (Nigeria) (Contribution: 100%)
  5. Ajeigbe, K.O., Onifade, A.A., Omotoso, D.R. , Enitan, S.S. and Olaleye, S.B. (2014). Anti-ulcerogenic activity of Aspilia Africana leaf extract: Roles of gastric acid oxidative stress and neutrophil infilteration, Africa Journal of Biomedical Research Vol. 19.2. pp 193-201 (Nigeria) (Contribution: 40%)
  6. Onifade, A.A., Emeka, G.J., Olaniyi, J.A. , Adeyanju, A.S. , Ojerinde, A.O. and Aiku, A.O. (2016). Non-reliability of Beta-2 Microglobulin and Neopterin as Immunological Markers of HIV Infection, Africa Journal of Biomedical Research Vol. 19.3. pp 205-212 (Nigeria) (Contribution: 50%)
  7. Onifade, A.A., Ojerinde, A.O. , Emeka, G.J. , Agbedana, E.O. and Oluogun, W.A. (2017). The role of IgG, IgA and IgM as immunological markers of HIV/AIDS progression, Journal of AIDS and HIV Research Vol. 9.7. pp 152-158 (United Kingdom) (Contribution: 50%)
  8. Onifade, A.A., Edem, V.F. and Arinola, O.G. (2018). Serum and sputum surfactants -A and -D in multidrug-resistant and drug sensitive tuberculosis patients, African Journal of Clinical and Experimental Microbiology Vol. 19.2. pp 88-92 (Nigeria) (Contribution: 70%)
  9. Onifade, A.A., Edem, V.F. , Ige, O.M. and Arinola, O.G (2018). TNF-alpha Levels in Serum and Mononuclear Cell Lysate of Nigerian Tuberculosis Patients at Diagnosis, Medical Journal of Zambia Vol. 45.1. pp 1-5 (Zambia) (Contribution: 60%)
  10. Onifade, A.A., Edem, V.F. and Arinola, O.G. (2018). Levels of Interleukin-6 In Mononuclear Cell Lysate of Nigerian Pulmonary Tuberculosis Patients, Tropical Journal of Health Sciences Vol. 25.3. pp 46-50 (Nigeria) (Contribution: 70%)

Research Focus:

My research focus is immunology of infectious diseases. I investigated the role of immunological markers in HIV infection progression and monitoring of herbal therapies. The research led to the safety studies of potential herbal therapy in animal model in acute and chronic phase when used alone or in combination with conventional medicines. Because monitoring of HIV infection are associated with problems, I investigated immunological markers that are potentially effective and less associated with problems. I also investigated the immunological markers that are potentially effective in making diagnosis and monitoring of complicated and un-complicated tuberculosis with drug or non-drug resistance effective. Because hands played major role in infection control, I investigated the presence of antimicrobial peptides in Nigerian residents and determined effectiveness of hand hygiene

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 Phone: 07034598900  Address:  Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
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