Dr. Bose E. ORIMADEGUN

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Name: Bose E. ORIMADEGUN

Designation: Senior Lecturer
Faculty: BASIC CLINICAL SCIENCES

Department: Chemical Pathology

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Brief Biography:

Bose E. Orimadegun graduated from the University of Ibadan with a degree in Biochemistry, an MSc. in Chemical Pathology, and a Ph.D. in Chemical Pathology. She started as lecturer II in the Department of Chemical Pathology, College of Medicine, University of Ibadan in 2014, was promoted to lecturer I in 2017 and is currently a senior lecturer since 2020. She is the postgraduate programmes coordinator of the Department of Chemical Pathology. 

Her studies are focused on nutrition and metabolism. She has spent the last few years researching how nutrition and lipid metabolism are altered in diseases. Some of these are detailed in her publications. She received a University of Ibadan Medical Education Partnership Initiative for Junior Faculty (UI-MEPI-J) award, which allowed her to travel to the Harvard School of Public Health for mentored research training. Many of her papers deal with lipids and metabolic intermediates in paediatric and adult diseases. She was the lead investigator and co-investigator in research on homocysteine in nephrotic syndrome, lipids in malaria infection in children, and coronary heart disease in Nigerian adults. Her research is attracting attention to rising dyslipidaemia among Nigerians by providing information on simple biomarkers for lipid-related disorders. Her research has the potential to transform the standard of care for lipid-related abnormalities in health and disease, and it will continue to help in relevant medical practices for the foreseeable future.

Research

1. Markers of Oxidative Stress and Vitamin E Levels in Young Female Adults with Dysmenorrhea: A Pilot Study

2. Relationships among Apolipoprotein A1 Gene Polymorphisms, Lipid Levels and Human Gene Expression in Malaria Infection

3. Predictive Values of Lipid Peroxidation Markers and Micronutrient Levels in Mid-Pregnancy for Newborns’ Maturity and Birthweight

Publications

1. Anetor JI, Adigun TO, Bolajoko EB, Anetor GO, Orimadegun BE, Akiibinu MO, et al. (2022). Deranged haembiosynthetic pathway in gasoline dispensers in Nigeria: Implications for risk of myeloproliferative disorders and chemoprevention. American Journal of Biopharmacy and Pharmaceutical Sciences; 2:2.

2. Orimadegun, B. E., (2021), 'Dyslipidaemia in African Children and Adolescents', in W. S.  Aronow (ed.), Management of Dyslipidemia, IntechOpen, London.

3. Orimadegun BE, Ogah F, Oyedele OB, Daodu OO (2021). Plasma Low-Density Lipoprotein Cholesterol Estimated by Friedewald Compared to Martin-Hopkins Equation in Nigerian Population. West African Journal of Medicine. Vol 38(3):255-261.

4. Orimadegun B. E., Odaibo G. O., Orimadegun A. E., Agbedana E. O. and Falade C. O. (2021). Malaria parasite density and plasma apolipoprotein A1 in symptomatic and asymptomatic infections. Journal of Vector Borne Diseases Vol 58 N0 4, 311-316.

5. Ogunbona, R.A., Orimadegun, B.E., Ogunlade, S.O., Fasanmade, A.A. and Agbedana, E.O. (2020).  Dyslipidemia and High Adiposity are Risk Factors for Osteoarthritis in Adults in Nigeria. American Journal of Biomedical Research Vol 8 No 1, 19-24.

6. Obilor, U., Charles-Davies, M.A., Okolo. S.U., Bolajoko, E.B., Orimadegun, B.E. and Ademola-Aremu O.O. (2019). Factor of sexual function in males occupationally exposed to bisphenol-A in a plastic industry in Ibadan. African Journal of Medicine and Medical Science Vol. 48 No. 3, 389-400. Click here

7. Orimadegun, B.E.,Awolude, O.A. and Agbedana, E.O. (2019). Markers of lipid and protein peroxidation among Nigerian university students with dysmenorrhea. Nigerian Journal of Clinical Practice 22 No. 2, 174-180.

8. Orimadegun, B., Bolajoko, E., Onyeaghala, A. and Ademola-Aremu, O. (2018). Quantitative analyses of phytochemical and trace elements contents of daily detox, herbal tea consumed in Nigeria. Journal of Medicinal Plants Research Vol. 12 No. 20, 289-295.

9. Orimadegun, A.E., Orimadegun, B.E. and Bamgboye, E.A. (2018). Short-term Persistence of Protective Maternally Acquired Immunity in Neonates Delivered by Primiparous Women in Ibadan, Nigeria. Ethiopian Journal of Health Sciences Vol. 28 No. 5, 447-456.

10. Orimadegun, A. E., Orimadegun, B. E. and Bamgboye, E. A. (2017). Non-protective immunity against tetanus in primiparous women and newborns at birth in rural and urban settings in Ibadan, Nigeria. Pan African Medical Journal Vol. 27 (Supp 3) No. 26, 1-6.

11. Orimadegun B. E.(2017). Lipid Metabolism in Malaria and Human Immunodeficiency Virus (HIV) Infections. In: Agbedana E.O, Anetor J.I, Ogundahunsi O.A (ed) Recent Advances in Nutrition and Metabolism.Ibadan University Press, University of Ibadan Chapter 10, pp 123-133. ISBN: 978-978-54045-1-7. 208 pages.

12. Orimadegun A.E. and Orimadegun B.E. (2015). Serum Apolipoprotein-A1 and Cholesterol levels in Nigerian Children with Plasmodium falciparum Infection. Medical Principles and Practice Vol. 24. No. 4: 318-324.

13. Orimadegun B. E., Orimadegun A. E., Ademola A. D., Agbedana E. O. (2014). Plasma homocysteine and B vitamins levels in Nigerian children with nephrotic syndrome. The Pan African Medical Journal Vol. 18. No. 107. Click here

14. Orimadegun AE, Ogunbosi BO, and Orimadegun BE. (2014). Hypoxaemia predicts death from severe falciparum malaria among children under 5 years of age in Nigeria: the need for pulse oximetry in case management. African Health Sciences Vol. 14. No. 2: 397 – 407. Click here

15. Orimadegun BE, Anetor JI, Adedapo DA, Taylor GO, Onuegbu JA, Olisekodiaka JM. (2007). Increased Serum Iron is associated with coronary heart disease among Nigerian Adults. Pakistan Journal of Medical Science Vol. 23. No. 4: 518-522. Click here

16. Orimadegun BE, Anetor JI, Adedapo DA, Taylor GO, Onuegbu JA, Olisekodiaka JM. (2011). Interrelationship of Serum Iron and Plasma Lipids in Adult Yorubas of the South-Western Nigeria with Coronary Heart Disease. Journal of Advancement in Medical and Pharmaceutical Science 5. No. 1: 22 – 25.

17. Orimadegun AE, Orimadegun BE, Adepoju AA. (2013). Immunity against tetanus infection, risk factors for non-protection and validation of a rapid immunotest kit among hospitalised children in Nigeria. Frontiers in Neurology Vol. 4. No. 142: 1-7.

Supervision

CURRENT STUDENTS
Masters Level

1. I am currently supervising 3 MSc students.

Doctoral Level

1. I am co-supervising one Ph.D. Student.

PREVIOUS STUDENTS

     Masters Level

1. Title: Cardiovascular Risk Factors in Nigerians with Osteoarthritis,
Student's Name: Razaq Abiodun Ogunbona
Examination Body: University of Ibadan
Year: 2018

2. Markers of Lipids and Deoxyribonucleic Acid Oxidation and Selenium level in Hepatitis B Infected Adults in Ibadan, Nigeria, 2019.

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