Dr. Yemi R. RAJI

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Name: Yemi R. RAJI

 Designation: Senior Lecturer
 Faculty: CLINICAL SCIENCES
 Department: Medicine
 Phone Number: +234 8033569700

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Biography:

Dr. Y.R.Raji, MBChB (Ife), MSc (Mich.), FMCP (Nig.) is a Lecturer in the Department of Medicine, College of Medicine, University of Ibadan and Honorary Consultant Nephrologist to the University College Hospital, Ibadan, Nigeria. He graduated from the Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria with a Bachelor of Medicine and Bachelor of Chirogy (MBChB) in 2004 and a Master’s degree in Human Genetics from the prestigious University of Michigan, USA. Had his Residence training at the Lagos University Teaching Hospital, Lagos Nigeria. He became a Fellow of the National Postgraduate Medical College of Nigeria, Nephrology Subspecialty in 2011. Dr. Raji’s research interests include genetics of kidney disease and its cardiovascular sequalae, burdens of kidney disease among the first degree relatives of patients with CKD, anaemia in chronic kidney disease, and systemic hypertension. Dr. Raji has been a Principal Investigator and Co-Investigator on many national and international research studies among which include the Humen Heredity and Health in Africa (H3Africa) Kidney Disease Research Network Project and the Genetics of Cardiometabolic Disease among Nigerians (NicGEN Study).  The H3Africa Kidney Disease study examined the genetic and environmental determinants of kidney disease among spectrum of CKD aetiology that include HIV, Hypertension, Diabetes mellitus, Glomerulonephritis and Sickle cell disease.  Dr. Raji has many publications in peer review journals. He is a member of many professional organizations that include International Society of Nephrology, American Society of Nephrology, African Association of Nephrology, Nigerian Association of Nephrology, Medical and Dental Consultants’ Association of Nigeria and Nigerian Medical Association.

Research

Current Research and Capacity Building Projects including Grants

1. Title: H3Afica Kidney Disease Research Network (HKDRN)
Funder: NIDDK
Brief Summary:  This collaborative multi-centered study across 6 African countries aims to identify the genetic determinants of kidney disease among the Sub-Saharan African. The study is currently undergoing data analysis and manuscript writing. The findings of this study will provide insight into the aetiopathogenesis of chronic kidney disease among Africans.
Role: Site PI
Collaborators: Prof. Akinlolu Ojo, Dr. Dwoma Adu, Prof. Babatunde Salak, Samuel Ajayi, Adebowale Ademola and others

2. Title: The Role of Dietary Factors in Chronic Kidney Disease Progression and Apolipoprotein L1 Nephropathy (DCA STUDY): Ancillary Study to the H3Africa Kidney Disease Research Network Cohort Study
Funder: NIDDK
Brief Summary:  This collaborative multi-centered study across 2 African countries aims to identify the role of diet as a genetic a modifier of rapid progression among patients with Chronic Kidney Disease.
Role: Site PI
Collaborators: Dr. Titi Ilori, Prof. Akinlolu Ojo, Dr. Dwoma Adu, Prof. Babatunde Salako, Prof Ifeoma Ulasi and others

Completed Research

i. Familial clustering of chronic kidney disease, risk factors for CKD and cardiovascular risk factors among first degree relative of patients with chronic kidney disease.

ii. Knowledge and attitude of first degree relative of patients with chronic kidney on kidney donation to affected family members with end stage renal disease.

iii. Knowledge, attitude and opinion of nephrology care givers to the growth of kidney transplantation in Nigeria

iv. Analysis of salivary urea and creatinine among patients with chronic kidney disease.

v. Iron status and clinical correlates in patients with chronic kidney disease.

vi. Cardiovascular risk stratification and cardiovascular outcomes among patients with chronic kidney disease

vii. Determinants of Acute Kidney Injury among patients undergoing surgical intervention in a tertiary healthcare centre

viii. Selective androgen receptor element responsive to doxorubicin for downstream gene regulation in prostate cancer

Publications

SELECTED PUBLICATIONS

1. Raji, Y.R. , Mabayoje, M.O. and Bello, B.T. 2015 Familial clustering of risk factors for cardiovascular disease among first-degree relatives of patients with chronic kidney disease in a sub-Saharan African population. Cardiovascular Journal of Africa (South Africa)

2. Osafo, C. , Raji, Y.R. , Rasooly, R.S. , Kimmel, P.L. , Burke, D. , Tayo, B.O. , Tiffin, N. , Ojo, A. , Adu, D. , Parekh, S. , Moxey-Mims, M.M. and H3Africa Kidney Disease Research Network Investigators as members of The H3Africa Consortium. 2015 Human Heredity and Health (H3) in Africa Kidney Disease Research Network: A focus on methods in sub-Saharan Africa.  Clinical Journal of American Society of Nephrology (United States of America)

3. Ajayi, S.O., Raji, Y.R. and Salako, B.L. 2016 Ethical and legal issues in renal transplantation in developing countries. Saudi Journal of Kidney Disease and Transplantation (Saudi Arabia)

4. Lasisi, T.J., Raji, Y.R. and Salako, B.L. 2016 Salivary creatinine and urea analysis in patients with chronic kidney disease: a case control study. Biomedical central Journal of Nephrology (United Kingdom)

5. Bello, B.T. , Raji, Y.R.  2016 Knowledge, attitudes and beliefs of first degree relatives of patients with chronic kidney disease towards kidney donation in Nigeria Saudi Journal of Kidney Disease and Transplantation (Saudi Arabia)

6. Osafo, C. , Raji, Y.R. , Winkler, C. , Parekh, S. , Olanrewaju, T. , Manmak, M. , Arogundade, F.A. , Ajayi, S.O. , Ulasi, I. , George, M. , Plange Rhule, J. , Rasooly, R.S. , Kimmel, P.L. , Burke, D. , Tayo, B.O. , Tiffin, N. , Ojo, A. , Adu, D. , Moxey-Mims, M.M. and and the H3Africa Kidney Disease Research Network Investigators as members of The H3Africa Consortium. 2016 Genomic approaches to the burden of kidney disease in sub - Saharan Africa- the Human Heredity and Health in Africa (H3A) Kidney Disease Research Network. Kidney International (United States of America)

7. Raji, Y.R., Ajayi, SO. , Bello, T.O. , Jinadu,O.Y. , Salako, B.L. , Arije, A. and Kadiri, S.  2017 Precipitants of acute exacerbation of chronic kidney disease: A single centre experience. Tropical Journal of Nephrology (Nigeria)

8. Raji, Y.R. , Abiona, T. and Gureje, O 2017 Awareness of hypertension and its impact on blood pressure control among The Pan African Medical Journal (Kenya)

9. Raji, Y.R. , Ajayi, S.O. , Gbadegesin, B.A. , Bello, T.O. and Salako, B.L 2017 Challenges facing the growth of kidney transplantation programmes in Nigeria: Perceptions and knowledge of the nephrologists and other healthcare providers. Indian Journal of Transplantation (India)

10. Adeoye, M.A. , Raji, Y.R. , Adebiyi, A. , Tayo, B.O. , Salako, B.L. , Ogunniyi, A. , Ojo, A. and Cooper R. 2017 Circadian Blood Pressure Variation amongst People with Chronic Kidney Diseases: A Pilot Study in Ibadan. Nigerian Postgraduate Medical Journal (Nigeria)

11. Owolabi, O.I, , Raji, Y.R. and Amodu, O.K. 2017 Nutritional status as a risk factor for renal impairment among in-school adolescents.  The Nigerian Journal of Public Health (Nigeria)

12. Raji, Y.R. , Mabayoje, M.O. , Bello, B.T. and Amira, C.O.  2018 Albuminuria and reduced estimated glomerular filtration rate among first-degree relatives of patients with chronic kidney disease in Lagos, Southwest Nigeria. Indian Journal of Nephrology (India)

13. Raji, Y.R. , Ajayi, S.O. , Ademola, A.F. , Lawal, T.A. , Ayandipo, O.O. , Adigun, T. and Salako, B.L. 2018 Acute kidney injury among adult patients undergoing major surgery in a tertiary hospital in Nigeria. Clinical Kidney Journal (United Kingdom)

14. Raji, Y.R. , Ajayi, S.O. , Aminu, O. , Abiola, B. , Efuntoye, O. , Salako, B.L. , Arije. A. and Kadiri. S. Outcomes of tunneled internal jugular venous catheters for chronic haemodialysis at the University College Hospital, Ibadan, Nigeria. The Pan African Medical Journal.

15. Raji, Y.R. , Ajayi, S.O. , Akingbola, T.S. , Adebiyi, O.A. , Adedapo, K.S. and Salako, B.L.  2018 Assessment of iron deficiency anaemia and its risk factors among adults with chronic kidney disease in a tertiary hospital in Nigeria. Nigerian Postgraduate Medical Journal. (Nigeria)

16. Raji, Y.R., Raji, K.O. , Bello, B.T. and Ekore, J.O.  2018 Effects of Gender on Patient's Satisfaction with Physician Care and Communication Skills in a Tertiary Hospital in Nigeria. Ife Psychologia (Nigeria).

17. Lawal, T.A. , Raji, Y.R. , Ajayi, S.O. , Ademola, A. , Ademola, A.F. , Ayandipo, O.O. , Adigun, T , Ogundoyin, O. , Olulana, D.I. , Asinobi, A.O. and Salako, B.L. 2019 Predictors and outcome of acute kidney injury after non-cardiac paediatric surgery. Renal Replacement Therapy

18. Kregel, S. , Bagamasbad, P. , He, S. , LaPensee, E. , Raji, Y.R. , Brogley, M. ,Chinnaiyan, A. , Ciesli,k. M. and Robins, D.M. 2020 Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element.  Nucleic acids research

19. Yusuf, T. , Raji, Y.R. , Daniel, A. , Bamidele, O.T. , Fasunla, A.J. and Lasisi, O.A.  2021 Effects of Chronic Kidney Disease on Olfactory Function: A Case–Control Study. Ear, Nose & Throat Journal Medicine

20. Raji, Y.R. , Ajayi, S.O. , Adeoye, A.M. , Amodu, O.K. , Tayo, B.O. and Salako, B.L.  2021 Fibroblast Growth Factor 23 (FGF 23) and intact Parathyroid Hormone (iPTH) as markers of mineral bone disease among Nigerians with non-diabetic Kidney Disease. African Health Sciences (Uganda)

Supervision

CURRENT STUDENTS

Fellowship Level - 5

PREVIOUS STUDENTS

 Masters Level - 7

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Soccer, seeing movies and visiting friends and families


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