Professor Ayotunde J. FASUNLA

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	Name: Ayotunde J. FASUNLA
	Designation: Professor
	Faculty: Clinical Sciences
	Department:Otorhinolaryngology
	Phone Number: : +234 803 374 0220
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Biography:

Ayotunde James Fasunla joined the services of the College of Medicine, University of Ibadan as a Lecturer I in March 2010 after the completion of his residency training in Otorhinolaryngology, Head and Neck Surgery. He has risen through the ranks of Senior Lecturer (2013) and Reader (2016) and became Professor of Otorhinolaryngology in 2019. He served as the Sub-Dean, Postgraduate in the Faculty of Clinical Sciences from 2014 - 2018. He was the Acting Head of the Department of Otorhinolaryngology from 2018 – 2020.

Ayotunde James Fasunla earned his Bachelor of Medicine and Surgery (MBChB) degree from the Obafemi Awolowo University, Ile-Ife in 1998. He also holds the Master of Science (MSc.) in Surgery from University of Ibadan in 2007 and Doctor of Human Medicine (M.D.) in Otorhinolaryngology from the University of Philipps, Marburg, Germany in 2011. He undertook his Fellowship/Residency training in Otorhinolaryngology at the University College Hospital, Ibadan, Nigeria. In 2016, he undertook a clinical programme at the Division of Otolaryngology, Groote Schuur Hospital, Cape Town, South Africa.   

Fasunla has a long-standing commitment to the development of otorhinolaryngology in Nigeria. He started to contribute as a Senior Registrar in Otorhinolaryngology in 2005 when he began teaching undergraduate medical students as part of their clinical postings in the Department of Otorhinolaryngology. He was the driving force behind the development of the curriculum for the Master of Science in Otorhinolaryngology (M.Sc.) in the department of Otorhinolaryngology, which he also presented for approval to the Board of the Postgraduate College of the University of Ibadan. He has served in a number of positions in the department, including Postgraduate Coordinator, Undergraduate Coordinator, and Acting Head of Department. He also teaches selected topics in Rhinology, Head and Neck, Pediatric Otorhinolaryngology and General Otorhinolaryngology. He is a qualified and an experienced internal and external examiner in higher education and has served on various academic and clinical committees, and review panels. In order to provide the greatest otorhinolaryngology healthcare for patients of all ages, he is passionate about teaching, enhancing the educational experience for students and putting research into practice.

Over the years, Fasunla has been more interested in clinical and laboratory research in otorhinolaryngology, head & neck surgery. He is passionate in conducting research that will produce and share knowledge essential for evidence-based otorhinolaryngologic practice. Additionally, he is concerned with the efficient translation of research-based conclusions into decisions that will benefit society as a whole. His long-term professional objectives are to become a renowned scholar who makes a significant contribution to the conduct of cutting-edge research that benefits the otorhinolaryngological health of the community and to become a distinguished expert who plays a key role in the delivery of evidence-based otorhinolaryngological care in the sub-Saharan African region. His main career interests and areas of sub-specialization are in rhinology, olfaction & gustation, facioplasty and head & neck surgery.

Resume

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Researches

Current Research and Capacity Building Projects including Grants

Title: Repurposing Povidone Iodine for the Treatment of Chronic Suppurative Otitis Media among Nigerian Children.                                      

Funder: Cure Within Reach, USA

Brief summary: Chronic suppurative otitis media (CSOM) is a leading cause of pediatric hearing loss and is associated with significant morbidity and mortality. Its mainstay of treatment is topical antibiotic eardrops, but with emerging resistance and increasing treatment failure, the need to investigate other treatment options has become necessary. Povidone-iodine is an antiseptic solution used for surgical scrub and perioperative skin preparation. Its efficacy in the treatment of CSOM is investigated in this study. It will be a one-year randomised clinical trial involving 390 children with uncomplicated CSOM aged 6 months to 14 years. Participants will be randomly assigned to one of three intervention groups: Group A [0.3% Ciprofloxacin aural drops and oral amoxicillin with clavulanic acid (30 mg/kg/day divided every 12 hours)]; Group B [5% aqueous povidone-iodine aural irrigation and oral amoxicillin with clavulanic acid (30 mg/kg/day divided every 12 hours)]; and Group C [5% aqueous povidone-iodine aural irrigation without oral antibiotics]. Each arm of the group will receive treatment for 4 weeks. Thereafter, assessments will be conducted at the end of 4 weeks and 3 months after commencement of treatment. Expected outcome measures will be resolution of otorrhoea, reduction in size or complete closure of tympanic membrane perforation, improvement in hearing threshold and negative ear culture results. Positive outcome from this study could provide an efficacious, cost effective and readily available treatment option for CSOM in children, particularly in low resource settings.

  

Title: Evaluation of olfactory function and quality of life of adults with chronic rhinosinusitis

Funder: Self sponsored

Brief summary: Olfactory impairment is a symptom of chronic rhinosinusitis (CRS), but despite its potential influence on general quality of life, it is rarely taken into account in the management of individuals with CRS. The study was designed to evaluate the olfactory function and quality of life of adults with chronic rhinosinusitis in Ibadan, Nigeria. It will be a case-control study of adult patients (18–65 years) with CRS attending otorhinolaryngology clinic, University College Hospital, Ibadan. The control group will be age- and gender-matched people who do not have CRS or nasal pathology. Relevant clinical data will collected with a structured questionnaire. The participants will undergo nasal endoscopy and also complete a Sino-nasal Outcome Test (SNOT)-22 questionnaire. Olfactory function will be objectively assessed using "Sniffin Sticks" as olfactory thresholds (OT), discrimination (OD), identification (OI), and Threshold Discrimination and Identification (TDI). Appropriate statistical analyses were done and level of statistical significance was set at a p-value of <0.05. The findings from this study is expected to provide information on whether or not the presence of olfactory impairment in CRS will worsen QoL or not. 

Publications

SELECTED PUBLICATIONS

1. Ogunleye, A.O., and Fasunla, A.J. (2004): Radiological changes and complications associated with nasal polyposis. West Afr J. Med. 23: 111 – 113.
2. Fasunla, J. and Lasisi, O.A. (2007). Sinonasal Malignancies: A 10-year review in a Tertiary Health Institution. Journal of the National Medical Association Vol. 99. No. 12: 1407-1410.
3. Fasunla, A.J., Ogunleye, A.O.A., and Ijaduola, G.T.A. (2007): Healthcare givers’ Skill and Foreign bodies in the ears of Children in the tropics. Int J Pediatr Otorhinolaryngol. 71: 191 – 195.
4. Fasunla, , Ibekwe, T., and Onakoya, P. (2007): Otomycosis in Western Nigeria. Mycoses. 51: 67 – 70.
5. Fasunla, A.J., Ibekwe, T.S., Afolabi, O.A., Onakoya, P.A., Oluwasola, O.A., Ogun, O.G., Adeoye, A.O. and Nwaorgu. O.G. (2008). Sinonasal paraganglioma: a case report. Oral and Maxillofacial Surgery 12. No. 2: 93-96.
6. Fasunla, A.J, Lasisi, O.A. (2009): Diagnostic challenges of laryngeal papillomatosis and its implications among children in developing countries. Int J Pediatr Otorhinolaryngol. 73: 593 - 595.
7. Fasunla, A.J. (2010): Challenges of Tracheostomy in Patients Managed for Severe Tetanus in a Developing Country. Int J Prev Med. 1:176-181.
8. Fasunla AJ, Adeosun AA, Afolabi AO, Nwaorgu OG (2011): Usefulness of behavioral test of hearing as a rapid public health screening tool for infants. J Pediatr Neurol. 9:29-33.
9. Fasunla, A.J., Greene, B.H., Timmesfeld, N., Wiegand, S., Werner, J.A. and Sesterhenn, A.M. (2011). A meta-analysis of the randomized controlled trials on elective neck dissection versus therapeutic neck dissection in oral cavity cancer. Oral Oncology 47. No. 5: 320-324.
10. Fasunla, A.J., Onakoya, P.A., Ogunkunle, O.O., Mbam, T.T. and Nwaorgu, O.G.B. (2011). Routine Electrocardiographic Request in Adenoidectomy: Is it necessary? Indian Journal of Otolaryngology and Head & Neck Surgery 63. No. 4: 330-335.
11. Fasunla, J.A., Hundt, W., Lutz, J., Förger, F., Thürmel, K. and Steinbach, S. (2012). Evaluation of smell and taste in patients with Wegener’s Granulomatosis. European Archives of Otorhinolaryngology 269. No. 1: 179-186.
12. Fasunla, A.J., Ogunbosi, B.O., Odaibo, G.N., Nwaorgu, O.G., Taiwo, B., Olaleye, D.O., Osinusi, K., Murphy, R.L., Adewole, I.F. and Akinyinka, O.O. (2014). Comparison of auditory brainstem response in HIV-1 exposed and unexposed newborns and correlation with the maternal viral load and CD4+ cell counts. AIDS 28. No. 15: 2223-2230.
13. Fasunla, A.J., Douglas, D.D., Adeosun, A.A., Steinbach, S. and Nwaorgu, O.G. (2014). Effect of strong fragrance on olfactory detection threshold. Otolaryngology Head Neck Surgery 151. No. 3: 438-442.
14. Fasunla AJ, Daniel A, Nwankwo U, Kuti KM, Nwaorgu OG, Akinyinka OO. (2016) Evaluation of olfactory and gustatory functions of HIV infected women. AIDS Research and Treatment. 2016:2045383 http:dx.doi.org/10.1155/2016/2045383.
15. Fasunla, A.J., Omisore, A.G., Nwaorgu, O.G. and Akinyinka, O.O. (2018). Long-term effects of maternal HIV infection and antiretroviral medications on the hearing of HIV-exposed infants. West African Journal of Medicine 35. No. 2: 90-96.
16. Fasunla, A.J., Nwankwo, U., Adebayo, A.M. and Nwaorgu, O.G. (2018). Association between sex, CD4 cell counts, antiretroviral medications, and olfactory and gustatory functions of HIV-infected adults. Otolaryngology - Head and Neck Surgery 158. No. 1: 90-99.
17. Fasunla, A.J., Nwankwo, U., Onakoya, P.A., Oladokun, A. and Nwaorgu, O.G.B. (2019) Gustatory function of pregnant and nonpregnant women in a tertiary health institution. Ear, Nose & Throat Journal 98. No. 3: 143 -148.
18. Daniel, A., Ogunkeyede, S.A., Fasunla, A.J., and Nwaorgu, O.G.B. (2020). Intraoperative dye test in total laryngectomy: A technique to reduce the incidence of pharyngocutaneous fistula. Nigerian Journal of Surgery. 26:127 – 129.
19. Ibekwe, T.S., Fasunla, A.J., and Orimadegun, B.E. (2020). Systematic review and Meta-analysis of smell and taste disorders in COVID-19. OTO Open. 4(3): 1 – 13.
20. Yusuf, T., Raji. Y.R., Lasisi, T.J., Daniel, A., Bamidele, O.T., Fasunla, A.J., and Lasisi, A.O. (2021). Predictors of taste dysfunction and its severity among patients with chronic kidney disease. Ear, Nose & Throat Journal. DOI: 10.1177/01455613211019708

Supervision

Not Available

Grants

Grant awards

Grant number: Dr Mercy Jatto
Title: Repurposing Povidone Iodine for the Treatment of Chronic Suppurative Otitis Media among Nigerian Children.
The goal of the project is to determine the efficacy of povidone iodine in the treatment of chronic Suppurative. 
Funder: Cure Within Reach, USA
Role: Co-Investigator
Period: April 2022 to March 2023

Grant number: RAB00048 PI: Ogunkoya
Title: Surveillance network constitution and establishment of rabies diagnosis laboratory at the College of Veterinary Medicine, Federal University of Agriculture, Abeokuta
The primary objective is to carry out a more comprehensive surveillance of rabies in a south western state of Nigeria in order to generate information and establish data on the current epidemiological status of the disease and the virus in the study area as well as to establish a sustainable model for rabies surveillance for the country at large.
Funder: Sanofi Pasteur SA
Role: Co-Investigator
Period: September 2017 to August 2018

Grant number: 2013-4692 PI: Akinyinka
Title: Postgraduate Academic Mobility for African Physician-Scientists Scholarship (PAMAPS)
The goal of the project is to build capacities and enhance performance of a new generation of physician-scientists through coordinated actions that will harness both professional and academic resources from six African HEIs. The members of the partnership are College of Medicine, University of Ibadan (COMUI), Nigeria; Addis Ababa University (AAU), Ethiopia; University of Cape Town (UCT), South Africa; University of Lagos (CMUL), Nigeria; University of Nairobi (CHS-UoN), Kenya and Faculty of Medicine and Biomedical Sciences, University of Yaoundé I (FMBS/UYI), Cameroon.
Funder: European Union/EACEA: Intra-ACP Academic Mobility Scheme Africa
Role: Co-Investigator
Period: April 2013 to April 2018

Grant number: G-97944-0 PI: Olugasa
Title: Research and Education in Epizootiology to Achieve More Effective and Efficient Prevention and Containment of Endemic, Emerging, and Neglected Zoonoses. The goal of the project is to improve postgraduate programmes for surveillance of human-animal diseases in West Africa and establishment of Centre for Control and Prevention of Zoonoses (CCPZ) at the University of Ibadan, Nigeria for the detection, isolation, and characterization of pathogens of emerging, endemic, and neglected zoonoses.
Funder: John D and Catherine T MacArthur Foundation
Role: Co-Investigator
Period: September 2011 to November 2016

Grant number: R24 TW008878 PI: Olaleye
Title: A mentored seed award was given from the major grant entitled Medical Education Partnership Initiative in Nigeria.
The goal of the mentored seed award was to investigate the effect of maternal HIV status and antiretroviral medications on the hearing of HIV exposed infants in Ibadan.
Funder: NIH
Role: Investigator/Mentee
Period: September 2012 – September, 2013

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