Basic Information
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Name: Oyindamola O. ABIODUN |
Faculty: BASIC CLINICAL SCIENCES |
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Email: This email address is being protected from spambots. You need JavaScript enabled to view it. |
Department:Pharmacology and Therapeutics | |
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Designation: Professor |
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Brief Biography: |
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Resume
- Name:Oyindamola Olajumoke ABIODUN
(b). Department: Pharmacology and Therapeutics
(c). Faculty: Basic Medical Sciences
(b). Present post (with date): Lecturer I (4 May, 2011)
II. Academic Qualification (with dates and granting bodies):
BSc Biological Sciences, University of Agriculture, Abeokuta 1995
MSc. Pharmacology and Therapeutics, University of Ibadan, Ibadan 1999
PhD Pharmacology, University of Ibadan, Ibadan, 2010
III.Scholarships, Fellowships and Prizes (with dates)
(a). Handling and Managing of Biological Materials Malaria March 2000
Research and Reference Reagent Resource Center (MR4),
Ouagadougou, Burkina Faso.
(b).WHO/TDR, Advanced Epidemiology Research Methods. July 2000
Navrongo, Ghana.
(c). MIM/TDR Antimalarial Drug Resistance Network Aug., 2002
In vitro susceptibility testing of antimalarial drugs. Contonou,
Republic of Benin.
(d). PhD fellowship supported by MIM/TDR Jan. 2000-April, 2006
(e). Pre-doctoral training fellowship, supported by Medicines for April, 2006 - July, 2007
Malaria Venture (MMV) and Swiss Tropical and Public Health
Institute Basel Switzerland
(f).Welcome Trust UK (Practical Aspects of Small Molecule Drug April, 2010
Discovery: at the Interface of Biology, Chemistry and Pharmacology),
Hinxton, Cambridge, UK.
(g). Post-doctoral fellowship supported by INSA JRD TATA Feb-May, 2011
Fellowship,Centre for International co-operation in science
(CICS), Chennai, India.
(h). Post-doctoral fellowship supported by COIMBRA Oct. - Dec., 2013
Group Fellowship, Department of Pharmacology, University
of Granada, Granada, Spain.
(i). Post-doctoral fellowship supported by TWAS/DFG, March - June 2014
Institute of Environmental Research of the Faculty of Chemistry
(INFU), Dortmund University of Technology, Germany.
Selected Travel fellowships
(i). International Organization of Chemistry in Development (IOCD) 1 - 4 Oct., 2006,
(ii). Royal Society of Tropical Medicine and Hygiene (RSTMH) 13 -15 Sept., 2007
(iii). Bill and Melinda Gates Foundation 28 Jan -1 Feb., 2007
(iv). Bill and Melinda Gates Foundation 20 - 28 Oct., 2008
(v). MIM/TDR 13 -18 Nov., 2005.
(vi). Bill and Melinda Gates Foundation 22 - 26 Mar., 2009
(vii). MIM/TDR 1 - 6 Nov., 2009
(viii). International Society of Antiviral Research (ISAR) 11 - 15 May, 2013
IV. Honours, Distinction and Membership of Learned Societies
Member, Royal Society of Tropical Medicine and Hygiene UK 2007
Grant from International Federation of Science (IFS), Sweden 2012 -2015
V. Details of Teaching Experience at the University Level 2002 to date
(a). Ladoke Akintola University of Technology, Ogbomosho 2002 - 2011
- Lecturer 2002 - 2004
- Lecturer II 2004 - 2006
- Lecturer I 2006 - 2011
Undergraduate Teaching & Final Year Project Supervision
- MBBS (Introductory, Block I & II postings) ` 2002- 2011
(b). University of Ibadan, Ibadan 2011 to date
- Lecturer I2011 to date
Undergraduate Teaching & Final Year Project Supervision
- MBBS (Introductory, Block I & II postings) 2011 – to date
Postgraduate Teaching & Supervision 2011 – to date
- PHA 701 - Investigative techniques
- PHA 712 - Organ Pharmacology
- PHA 707 - Inflammation
- PHA 711 - Project
(c). Courses Taught at Ladoke Akintola University of Technology, Ogbomosho (LAUTECH)
- Introduction to Pharmacology
- Autonomic nervous system
- Chemotherapy
- Endocrine Pharmacology
- Toxicology
(d) Courses Taught at University of Ibadan, Ibadan (UI)
MBBS (Introductory, Block I & II postings)
How drugs act, therapeutic index, factors affecting drug response, pharmacogenetics, dose-response relationships. Purgatives and anti-diarrheal drugs, anti-emetics, drug treatment of bronchial asthma. Drug treatment of inflammatory bowel disease. Histamine and antihistamines, serotonin, kinins, anti-emetics, hematinics and purgatives, local and general anesthesia.
B. Pharmacy
(i). PHA 301 - Introductory Pharmacology
(ii). PHA 302 - Autonomic Nervous System I
(iii). PHA 304 - Pharmacology of haemopoetic system and gastrointestinal tract
(iv). PHA 401 - Pharmacology of cardiovascular system
(v). PHA 502 - Toxicology
(vi). PHA 403 - Chemotherapy
B. Physiotherapy, B.Sc Nursing
(i). PHA 301 – Introductory Pharmacology
(e). Supervision of undergraduate final year projects
Number of B. Laboratory Science or B. Pharmacy Students supervised from 2009 to date - 7
(f). Postgraduate Projects Supervision
6 M.Sc. project supervised 2010 to date
1 M.Phil/Ph.D` being supervised 2014
(d). Reviewer in peer review journals
Pharmaceutical Biology
Macedonian Journal of Medical Sciences
(e). Administrative appointments
(i). Acting Head of Department of Pharmacology and Therapeutics, Ladoke 2010 - 2011
Akintola University of Technology, Ogbomosho (LAUTECH)
(ii). Member, Academic Board, College of Health Sciences, LAUTECH 2010 – 2011
(iii). Member, Departmental Finance Committee 2012 to date
(iv). Member, Faculty of Basic Medical Sciences Finance Committee 2014 to date
Researches
(A). Research Completed
1. Group development grant: Inter-institution collaboration and studies on combination therapy: drug resistance, immunology and vaccine development for malaria
Funding agency: MIM/TDR
Principal Investigator: Prof. AMJ Oduola
Role: MSc. Trainee
2. Antimalarial drug resistant network: defining and monitoring drug resistant
Plasmodium falciparum infections in southwest Nigeria
Funding agency: MIM/TDR
Principal Investigator: Prof . Grace Gbotosho
Role: Ph.D Trainee
3. Identification of potential antimalarial compounds from Nigeria Ethnomedicine
Funding agency: MIM/TDR
Principal Investigator: Prof. Edith Ajaiyeoba
Role: Ph.D Trainee
4. A multicenter, randomized parallel group study to assess the efficacy, safety and tolerability of a single 400mg PO dose of oxibendazole suspension versus a single 500mg PO dose of mebendazole tablet in the treatment of intestinal helminthic infections in children ages 2 -17 years.
Funding agency: GlaxoSmithKline
Principal Investigator: Prof. Catherine Falade
Role: Ph.D Trainee
5. Preclinical investigation of medicinal plants for antimalarial, antitrypanosomal and cytotoxicity activites and drug interaction studies
Funding agency: Medicines for Malaria Venture and Swiss Tropical Institute
Investigator: Dr. Oyindamola Abiodun
6. Isolation and structure elucidation of antioxidant and antimicrobial principles in Terminalia catappa and Vitex doniana
Funding agency: Centre for International co-operation in science (CICS), Chennai, India
Investigator: Dr. Oyindamola Abiodun
(B). In Progress (2013 - 2015) - Investigator
7. Identification of antiparasitic compounds in Terminalia catappa and Vitex doniana from Nigeria ethnomedicine
Funding agency: International Federation of Science (IFS), Swedeen.
Principal Investigator: Dr. Oyindamola Abiodun
8. Evaluation of the molecular mechanism of action of anti-inflammatory activity of four selected Nigerian plants in rat model of TNBS colitis
Funding agency: by COIMBRA group Fellowship, University of Granada, Spain
Investigator: Dr. Oyindamola Abiodun
9. Identification of antiplasmodial components of Terminalia catappa and Trema orientalis
Funding agency: TWAS/DFG, Technical University of Dortmund, Germany
Investigator: Dr. Oyindamola Abiodun
(C). Dissertations and Thesis
Oduola O.O. (1999). The efficacy and safety of chloroquine and promethazine combinations in the treatment of chloroquine resistant P. berghei in gravid albino mice. MSc.
Oduola O.O. (2010). Identification of antimalarial agents in Nigerian ethnomedicine and prolongation of clinical usefulness of standard antimalarial drugs. Ph.D
Publications
(a). Manuscript in peer – review journals
1. Ajaiyeoba, E.O., Osowole, O.S., Oduola, O.O., Ashidi J.S., Akinboye, D.O., Gbotosho, G.O., Falade, C.O., Ogundahunsi, O.A., Fawole, O.I., Bolaji, O.M., Falade, M.O., Oladepo, O.O., Itiola, O.A and Oduola, A.M. (2002). Nigerian antimalarial ethnomedicine 2: Ethnobotanical surveys of herbal remedies used in the treatment of febrile illnesses in the middle belt of Nigeria. Journal of Phytomedicine and Therapeutics 7 (1&2): 26-39.
2. Ajaiyeoba, E.O., Oladepo, O., Fawole, O.I., Bolaji, O.M., Akinboye, D.O., Ogundahunsi, O.A., Falade, C.O., Gbotosho, G.O., Itiola, O.A., Happi, T.C., Ebong, O.O., Ononiwu, I.M., Osowole, O.S., Oduola, O.O., Ashidi, J.S. and Oduola, A.M. (2003). Cultural categorization of febrile illnesses in correlation with herbal remedies used for treatment in Southwestern Nigeria. Journal of Ethnopharmacology, 85 (2-3): 179-85.
3. Oduola, O.O., Happi, T.C., Gbotosho, G.O., Ogundahunsi, O.A., Falade, C.O., Akinboye, D.O., Sowunmi, A. and Oduola, A.M. (2004). Plasmodium berghei: efficacy and safety of combinations of chloroquine and promethazine in chloroquine resistant infections in gravid mice. African Journal of Medicine and Medical Sciences, 33 (1): 77-81.
4. Ajaiyeoba, E., Ashidi, J., Abiodun, O., Okpako, L., Ogbole, O., Akinboye, D., Falade, C., Bolaji, M., Gbotosho, G., Falade, M., Itiola, O., Houghton, P., Wright, C. and Oduola, A. (2004). Antimalarial Ethnobotany: In vitro antiplasmodial activity of seven plants identified in the Nigerian middle belt. Pharmaceutical Biology, 42(8): 588-591.
5. Ajaiyeoba, E.O., Falade, C.O., Fawole, O.I., Akinboye, D.O., Gbotosho, G.O., Bolaji, O.M., Ashidi, J.S., Abiodun, O.O., Osowole, O.S., Itiola, O.A., Oladepo, O., Sowunmi, A. & Oduola, A.M. (2004). Efficacy of herbal remedies used by herbalists in Oyo State Nigeria for treatment of Plasmodium falciparum infections--a survey and an observation. African Journal of Medicine and Medical Sciences, 33(2): 115-9.
6. Awe, E.O., Adeniyi, B.A., Olajide, O.A., Wakeel, O.K., Abiodun, O.O and Makinde J.M. (2004). Studies on antibacterial properties of Russelia equisetiformis (Schlect & Cham) Scrophulariacae. Science Focus 6: 131-133.
7. Dada-Adegbola, H.O., Falade, C.O., Oluwatoba, O.A., Abiodun, O.O. (2004). Gastrodiscoides hominis infection in a Nigerian-case report. West African Journal of Medicine, 23 (2): 185-6.
8. Osowole, O., Ajaiyeoba, E., Bolaji, O., Akinboye, D., Fawole, O., Gbotosho, G., Ogbole, O., Ashidi, J., Abiodun, O., Falade, C., Sama W., Oladepo, O., Itiola, I. and Oduola, A. (2005). A survey of treatment practices for febrile illnesses among Traditional Healers in the Nigerian Middle Belt Zone. African Journal of Traditional Complimentary and Alternative Medicine, 2 (3): 337 – 344.
9. Ajaiyeoba, E. O., Bolaji, O. M., Akinboye, D. O., Falade, C. O., Gbotosho, G. O., Ashidi, J. S., Okpako, L. C., Oduola, O. O., Falade, M. O., Itiola, O. A., Houghton, P. J., Wright, C. W., Ogundahunsi, O. A. and Oduola, A. M. J. (2005). In vitro anti-plasmodial and cytotoxic activities of plants used as antimalarial agents in the southwest Nigerian ethnomedicine. Journal of Natural Remedies, 5/1: 1-6.
10. Ogungbamigbe, T.O., Ogunro, P.S., Elemile, P.O., Egbewale, B.E., Olowu, O.A. and Abiodun, O.O. (2005). Prescription patterns of antimalarial drugs among medical practitioners in Osogbo metropolis, south -west Nigeria. Tropical Medicine and Health, 33(4): 201-208.
11. Ebong, O.O., Ajaiyeoba, E.O., Ononiwu, I. M., Eteng, M. J., Akinboye, D.O., Gbotosho, G.O., Falade, C.O., Osowole, O.S., Happi, C, Fawole, O.F., Ogundahunsi, O.A.T., Agbadwa, I. M., Oduola, O. O & Oduola, A.M.J. (2005). Contribution of indigenous health care givers to the herbal management of febrile illnesses in Rivers state, south-South Nigeria. West African Journal of Pharmacology and Drug research 21: 48-54.
12. Ajaiyeoba, E.O., Abiodun, O.O., Falade, M.O., Ogbole, N.O., Ashidi, J.S., Happi,C.T. & Akinboye, D.O. (2006). In vitro cytotoxicity studies of 20 plants used in Nigerian antimalarial ethnomedicine. Phytomedicine, 13(4): 295-298.
13. Akinboye, D.O., Ovansa, J.U., Okwong, E., Fawole, O., Agbolade, O.M., Akinboye, O.O., Amosu, A.M., Atulomah, N.O.S, Happi, T.C., Oduola, O.O., Owodunni, B.M., Rebecca, S.N., Falade, M. and Okwong, E. (2009). Malaria and genetic polymorphisms of haemoglobin genotypes and ABO Blood groups. Acta SATECH 3(1): 122-131.
14. Kiboi, D.M., Irungu, B.N., Langat, B., Wittlin, S., Brun, R., Chollet, J., Abiodun, O., Nganga, J.K., Nyambati, V.C.S., Rukunga, G.M., Bellf, A., and Nzila, A. (2009). Plasmodium berghei ANKA: Selection of resistance to piperaquine and lumefantrine in a mouse model. Experimental Parasitology, 122 (3): 196–202.
15. Akinboye, D.O., Okwong, E., Ajiteru, N., Fawole, O., Agbolade, O.M., Ayinde, O.O., Amosu, A.M., Atulomah, N.O., Oduola, O., Owodunni, B.M., Rebecca, S.N and Falade, M. (2010) Onchocerciasis among the inhabitants of Ibarapa local government community of Oyo state, Nigeria. Biomedical Research, 21(2): 174-178.
16. Abiodun, O.O., Gbotosho, G.O., Ajaiyeoba, E.O., Happi, C.T., Hoefer, S., Wittlin, S., Sowunmi, A., Brun,R. and Oduola, A.M.J. (2010). Comparison of SYBR Green I-, PicoGreen-, and [3Hhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Abiodun%20O%22%5BAuthor%5D">Abiodun, O., Gbotosho, G., Ajaiyeoba, E., Happi, T., Falade, M., Wittlin, S., Sowunmi, A., Brun, R. Oduola, A (2010). In vitro antiplasmodial activity and toxicity assessment of some plants from Nigerian ethnomedicine. Pharmaceutical Biology, 49(1):9-14.
18. Awe, E.O., Kolawole, S.O., Wakeel, K.O., Abiodun, O.O. (2011). Antidiarrheal activity of Pyrenacantha staudtii Engl. (Iccaci naceae) aqueous leaf extract in rodents. Journal of Ethnopharmacology, 137(1): 148-53.
19. Abiodun, O.O., Gbotosho, G.O., Ajaiyeoba, E.O., Brun, R., Oduola, A.M. (2012). Antitrypanosomal activity of some medicinal plants from Nigerian ethnomedicine. Parasitology Research, 110(2): 521-6.
20. Gbotosho, G.O., Happi, C.T., Woranola, O., Abiodun, O.O., Sowunmi, A. and Oduola, A.M. (2012) Interaction between ciprofloxacin and chloroquine in mice infected with chloroquine resistant Plasmodium berghei : Interaction between ciprofloxacin and chloroquine. Parasitology Research, 110(2): 895-9.
21. Abiodun, O.O., Brun, R. and Wittlin, S. (2013). In vitro interaction ofartemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains. Malaria Journal, 12: 43. DOI: 10.1186/1475-2875-12-43.
22. Ajaiyeoba, E.O., Ogbole, O.O., Abiodun, O.O., Ashidi, J.S., Houghton, P.J., Wright, C.W. (2013). Cajachalcone: An Antimalarial Compound from Cajanus cajan Leaf Extract. Journal of Parasitology Research, 703781. doi: 10.1155/2013/703781. Epub 2013 Jul 18.
23. Fadare, D.A., Abiodun, O.O. andAjaiyeoba, E.O. (2013). In vivo antimalarial activity of Trichilia megalantha harms extracts and fractions in animal models. Parasitology Reasearch, 112 (8):2991-5.
24. Ojurongbe, O, Lawal, OA, Abiodun, OO, Okeniyi, JA, Oyeniyi, AJ, Oyelami, OA. (2013). Journal of Infectious Disease of Developing Countries, 7 (12): 975-82.
25. Badejo, J.A., Abiodun, O.O., Akinola, O., Happi C.T., Sowunmi, A., Gbotosho, G.O. (2014). Interaction between rifampicin, amodiaquine and artemether in mice infected with chloroquine resistant Plasmodium berghei. Malaria Journal, 13(1): 299.
26.Abiodun O.O., Akinbo J., Ojurongbe O. (2014). The effect of lopinavir/ritonavir on the antimalarial activity of artemether or artemether/lumefantrine in a mouse model of Plasmodium berghei. Journal of Chemotherapy, 2014 Jan 16:1973947813Y0000000158. [Epub ahead of printhttp://www.ncbi.nlm.nih.gov/pubmed?term=Agnihotri%20VK%5BAuthor%5D&cauthor=true&cauthor_uid=22780302">Agnihotri V.K., Gulati A. Ajaiyeoba E.O. and Singh B.Antimicrobial activity of Terminalia catappa and Vitex doniana (Accepted for publication in African Journal of Medicine and Medical Sciences).
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