Prof. Oyeronke A. ODUNOLA

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Name: Oyeronke A. ODUNOLA

Designation: Professor

 Faculty: BASIC MEDICAL SCIENCES
 Department: Biochemistry
 Phone Number: +2348023387512

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Biography:

Oyeronke Adunni ODUNOLA (née OSOWOLE)

Professor Oyeronke A. Odunola is the Dean, Faculty of Basic Medical Science, College of Medicine, University of Ibadan, Ibadan, Nigeria. She is the Director of Research, Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, the immediate past Head, Department of Biochemistry, immediate past Director, Research Management Office and Association of Commonwealth Universities (ACU) Ambassador at the same University. She has also served the University as Hall Warden (Obafemi Awolowo and Queen Elizabeth II Halls) and in several committees and panels.

She obtained her BSc, MSc and PhD degrees in Biochemistry from University of Ibadan in 1984, 1986 and 1990 respectively. She emerged the best graduating student at both the B.Sc. and M.Sc. levels.

Professor Odunola has thirty-seven (37) years of teaching and research experience in cancer research and molecular biology, environmental toxicology, immune-oncology, nutritional genomics and climate change. She also has expertise in research administration and management, and community engagement. She is a recipient of International Agency for Research on Cancer (1985) and African Petroleum (1989) Travel Grants, University of Ibadan Senate Research Grants (1996, 1999 & 2000). She led the teams that won the DFID, UK-funded Climate Impact Research Capacity and Leadership Enhancement (CIRCLE) Implementation Grant for University of Ibadan (2017, 2018 & 2019). She has successfully supervised twelve (12) PhD theses, one hundred and fifty (150) MSc dissertations and over two hundred and fifty (250) undergraduate projects. Furthermore, she has organised and coordinated several training workshops on manuscript writing, grantsmanship, data management and commercialization, researcher’s development and research ethics, mentoring, research administration and financial management. She has also facilitated a couple of cancer awareness and screening programmes.

Prof. Odunola has served as External Examiner to several Universities in Nigeria and to University of the Western Cape, Bellville, South Africa; University of South Africa, South Africa and University of Ghana, Legon, Ghana, and as External Assessor for University of Ghana, Legon, Ghana, University of Development Studies, Tamale, Ghana and University of the West Indies, Kingston, Jamaica. She also served as a mentor on the African Women in Agricultural Research and Development (AWARD) and Africa Graduate Mentorship and Coaching (AGMCP) programmes respectively.

She has coedited a book on ‘Building the Next Generation of Mentors in Africa: Principles, Practices & Impacts’. In addition, she has a total of one hundred and six (106) publications in reputable national and international peer-reviewed journals, seventy (70) abstracts in conference proceedings, and twenty-five (25) plenary / invited lectures to her credit.

Professor Odunola is a member of Organisation for Women in Science in Developing World (OWSDW), Science Association of Nigeria; West African Research and Innovation Management Association (WARIMA), African Society of Drosopillists (ASD), Society of Toxicology, USA and Society of Research Administrators International (SRAI), USA. Professor Odunola is an honorary Fellow of the Chemical Society of Nigeria, Kwara Chapter, Member and one of the Technical Advisers, Dove-Haven Foundation, and a Member of the Board of Trustees of Ellen Adeyinka Anjorin Cancer Foundation.

Resume

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Research

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Publications

SELECTED PUBLICATIONS

1. Odugbesan, E.A., Osowole, O.A. and Uwaifo A.O. (1988). Effect of antiserum against aflatoxin B1 induced lysogenesis. Mutation Research, 209, 7-11.

2. Osowole, O.A.; Tonukari, J.N. and Uwaifo, A.O (1992). Isolation and partial characterization of pigeon pea protease inhibitor: - Its effect on genotoxic action of aflatoxin B1. Biochemical Pharmacology, 43(8), 1880 -1882.

3. Odunola, O.A. (1997). Individual and combined genotoxic response of boric acid and aflatoxin B1 in Escherichia coli, PQ 37. East African Medical Journal, 74(8), 499-502.

4. Odunola, O.A. and Uwaifo, A.O. (2000). Immune response to aflatoxin B1 - histone H1 African Journal of Medicine and Medical Sciences, 29, 105-110.

5. Odunola, O.A. (2003). Comparative effects of some local food condiments on sodium arsenite-induced clastogenicity. African Journal of Medicine and Medical Sciences, 32, 75-80.

6. Odunola, O.A., Uka E., Akinwumi, K.A., Gbadegesin, M.A., Osifeso, O.O. and Ibegbu, M.D. (2008). Exposure of laboratory mice to domestic cooking gas: Implications for toxicity. Internationl Journal of Environmental Research and Public Health, 5 (3): 172-176.

7. Odunola, O.A, Akinwunmi, K.A, and Ibegbu, M.D. (2011) The influence of garlic and Spondias mombin on sodium arsenite induced clastogenicity and hepatogenicity in rats. The Pacific Journal of Science and Technology, 12(2):401-409.

8. Odunola O.A, Gbadegesin M.A, Owumi S.E, Somade O.T. (2012). Induction of Micronuclei in Bone Marrow Cells and Hepatotoxicity of one of the most common Over-the – Counter Pyrethroid Insecticides Products in Nigeria. Toxicology and Environmental Chemistry: 94(9), 1822-1831.

9. Muhammad A., Odunola, O.A., Farooq, A.D., Rasheed, H., Mesaik, A.M., Choudhary, M.I., Channa, I.S., Khan, S.A.and Erukainure, O.I. (2013): Molecular Mechanism of Antiproliferation Potential of Acacia Honey on NCI-H460 Cell Line. Nutrition and Cancer: 65(2), 296-304.

10. Odunola, O.A, Muhammad A., Farooq, A.D., Dalvandi, K., Rasheed, H., Choudhary, M.I. and Erukainure, O.I. (2013). Comparative assessment of redox sensitive biomarkers due to acacia honey and sodium arsenite administration in vivo. Mediterranean J Nutrition and Metabolism 6, 119-126.

11. Gbadegesin, M.A, Owumi, S.E, Akinseye, V. Odunola, O.A (2014). Evaluation of hepatotoxicity and clastogenicity of carbofuran in male Wistar rats. Food and Chemical Toxicology: 65, 115–119.

12. Gbadegesin MA, JO Olugbami, NO Onwukwe, AM Adegoke and Odunola, O.A. (2017). Ethanol extract of Terminalia avicennioides root bark protects against cadmium toxicities in rats. African Journal of Biomedical Research: 20 (2), 165-172.

13. Olugbami JO, Damoiseaux R, France B, Gbadegesin MA, Stieg AZ, Sharma S, Odunola A, and Gimzewski JK. (2017). Atomic force microscopy correlates antimetastatic potentials of HepG2 cell line with its redox/energy status: Effects of curcumin and Khaya senegalensis. Journal of Integrated Medicine: 15(3), 214-230.

14. Samuel E.S., Gbadegesin, MA., Owumi SE, and Odunola, O.A. (2017). Sodium arsenite-induced reproductive toxicities in male Wistar rats: role of Tridax procumbens leaf extract. Bulletin of Animal Health and Production in Africa: 65(3), 501-508.

15. Gbadegesin MA, Udegbunam EC, Olugbami JO, Adegoke AM and Odunola O.A. (2018). Hepatotoxicity and Clastogenicity of dichlorvos at high doses in male Wistar rats. African Journal of Medicine and Medical Sciences: 47(2), 185 – 194

16. Karigidi, M. E., Olotu, O. O., Osawere, O., Olugbami, J. O., Adegoke, A. M. and Odunola, O. A. (2020). Antioxidant capacities and phytoconstituents of fractions of ethanol extract of Cymbopogon citratus (DC.) stapf: Inhibition of Iron II (Fe2+) - induced lipid peroxidation in rat colon homogenate. African Journal of Biomedical Research, 23: 429 – 436.

17. Adegoke A.M., Gbadegesin M.A., and Odunola O.A. (2020). Hepato-Genoprotective Activities of Methanol Extract of the Stem Bark of Adansonia digitata in Wistar Rats Challenged with Sodium Arsenite. Niger. J. Physiol. Sci. 35: 173 – 179.

18. Oyibo, A., Gbadegesin M.A., and Odunola O.A. (2021). Ethanol extract of Vitellaria paradoxa (gaertn, f) leaves protects against sodium arsenite-induced toxicity in male wistar rats. https://doi.org/10.1016/j.toxrep.2021.03.035

19. Odunola, O.A., Omotosho, I.O., Gbadegesin, M.A., Olugbami, J.O., Adegoke, A.M., Adebisi, O.A., Momoh, I.S. and Adobor, C.A. (2022). Induction of metastatic cervical cancer via HeLa cell xenografts in female Wistar rats: Modulatory Effect of Yoyo Bitters. Archives of Basic and Applied Medicine 10(1): 32-40.

20. Oyibo, A., Abolaji, A. O., Omoboyowa, A.,Odunola, O. A. (2023). Vitellaria paradoxa inhibits arsenic-induced toxicity in Drosophila melanogaster via the augmentation of antioxidant system. Toxicology, Toxicology 494(2):153590 DOI: 10.1016/j.tox.2023.153590

Supervision

a. CURRENT STUDENTS

    Masters Level: 6

    Doctoral Level: 5

PREVIOUS STUDENTS (Selected)

     Masters Level: 150 Students

     Doctoral level: 12 Students

1. Moyib, K. (2010): Molecular Characterization and Comparative genomics of resistance gene analogues in Cassava (Manihot esculenta Crantz).

2. Ola-Davies, O.E (2010): Antigenotoxic Activities of Extracts of Spondias mombin L. (Anacardiaceae) and Chromolaena odorata L. (Asteraceae).

3. Akin-Idowu, P.E (2013): Phenotypic and Molecular Characterisation of Some Amaranthus Accessions and Hepatoprotective Activity of Their Ethanol Extract on Sodium Arsenite-Induced Toxicity in Male Ra

4. Muhammad, A. (2015): Anticancer, Antioxidant and Immuno-modulatory Effects of “Acacia Honey” in some Cancer Cell Line

5. Akinwumi A. (2015): Cytotoxicity of Hexavalent Chromate Compounds in CH310T1/2 Cells and Cytomodulation by Sodium Arsenite and Methanol Extract of Rauvoltia vomitora (A.fzel) in mice.

6. Adewale, A (2016): Cytomodulation of acrylamide-induced toxicity by extracts of Basella alba Linn. in vivo and in vitro models of carcinogenicity.

7. Olugbami, J.O (2017): Cytomodulatiom of Sodium arsenite and Aflatoxin B1- Induced Cellular Injuries by Curcumin and Ethanol Stem Bark Extract of Khaya senegalensis (Desr.) A. Juss.

8. Adegoke, A.O (2018): Cytoremediation of Sodium arsenite-induced toxicities by extracts of Adansonia digitata in Cell Lines and Wistar rats.

9. Oyibo, A. (2021): Cytoremediative potentials of Vitellaria paradoxa (Gaertn. C.F) in arsenic-induced toxicity in Wistar rat, Harwich fruit fly and its antiproliferative activity in MCF-7 cells.

10. Karigidi, M. E. (2022): Chemopreventive effects of Cymbopogon citratus (DC.) Stapf. Extract on 1,2-dimethylhydrazine-induced Colon Toxicity in Mice and Colorectal Cancer (HT-29) Cells.

11. Ola, O. S. (2022): Anti-leukaemic and hepatoprotective effects of Eulophia gracilis extracts on benzene-induced leukaemia in rat and its selective cytotoxicity on cancer cell lines.

12. Samuel, S. (2023): Cytoprotection by leaf extract of Tridax procumbens (LINN.) in embryonic mouse, HEPG2 and PANC-1 cell lines and arsenite-induced toxicity in rats.

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Other Interest/Hobbies

Prof Odunola 2

Gardening, Drawing, Photography and Singing. She also plays chess and badminton.

 


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